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MLS001164888 (CID 24761053) - Compound BioActivity Data
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BioActivity Outcomes:
Active(109)
 
 
Inactive(442)
 
 
Inconclusive(32)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(37)
 
 
 
Esterase lipa..(10)
 
 
 
TRP 2(9)
 
 
 
PRK00058(5)
 
 
 
CAP ED(5)
 
 
BioAssay Types:
Screening(393)
 
 
 
 
Confirmatory(170)
 
 
 
 
 
Literature(12)
 
 
 
BioActivity Types:
Potency(123)
 
 
 
 
 
IC50(31)
 
 
 
 
EC50(9)
 
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 533    Data Row: 584   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49664925]
Potency 0.1169Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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2
[SID49664925]
Potency 0.1312Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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3
[SID49664925]
EC50_uM 2.38Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
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4
[SID49664925]
AC50_uM 3.35VEID(2) R110 Enzymatic Primary HTS to identify Inhibitors of Caspase 6 Measured in Biochemical System Using Plate Reader - 7052-01_Inhibitor_Dose_CherryPick_Activity [AID720632, Type: confirmatory]Caspase 6, apoptosis-related cysteine peptidase [Homo sapiens] [gi:13325293]
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5
[SID49664925]
EC50 3.534Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA) [AID623963, Type: confirmatory]MSRA protein [Bos taurus] [gi:73586699]
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6
[SID49664925]
Potency 3.5481qHTS Assay for Inhibitors of the HIV-1 protein Vpr [AID651644, Type: confirmatory]Vpr [Human immunodeficiency virus 1] [gi:28872817]
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7
[SID49664925]
EC50_MICROM 4.52Confirmation dose response of additional hit compounds from high-throughput yeast screen for caloric restriction mimetics that inhibit age-related superoxide. [AID504927, Type: confirmatory]
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8
[SID49664925]
Potency 4.7444qHTS for Inhibitors of WRN Helicase [AID651768, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
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9
[SID137291996]
EC50 4.926Late stage absorbance-based biochemical dose response assay for activators of Methionine sulfoxide reductase A (MsrA) [AID624497, Type: confirmatory]MSRA protein [Bos taurus] [gi:73586699]
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10
[SID49664925]
IC50 5.962Fluorescence-based biochemical high throughput screening dose response assay to identify inhibitors of Crimean-Congo Hemorrhagic Fever (CCHF) viral ovarian tumor domain protease (vOTU): Pep-AMC substrate [AID720578, Type: confirmatory]putative polyprotein [Crimean-Congo hemorrhagic fever virus] [gi:76364066]
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11
[SID49664925]
Potency 7.9433qHTS for Small Molecule Inhibitors of the ERG Ets/DNA interaction [AID624246, Type: confirmatory]transcriptional regulator ERG isoform 3 [Homo sapiens] [gi:343478176]
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12
[SID49664925]
Potency 8.1961qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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13
[SID49664925]
Potency 10qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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14
[SID49664925]
AC50_uM 10.05Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity [AID449750, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
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15
[SID49664925]
Potency 10.3225qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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16
[SID49664925]
IC50_MT1-MMP(HT1080)_Mean 10.5Dose Response confirmation of uHTS hits for a small molecule inhibitors of MT1-MMP activation in a fluorescence assay set 2 [AID652242, Type: confirmatory]matrix metalloproteinase-14 preproprotein [Homo sapiens] [gi:4826834]
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17
[SID49664925]
EC50_uM 11.85Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation [AID434968, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
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18
[SID49664925]
Potency 12.5893qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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19
[SID49664925]
Potency 12.5893qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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20
[SID49664925]
Potency 14.1254qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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