CHEMBL279403 (CID 24749598) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srsx(4)
 
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
IC50(1)
 
 
Ki(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103540614]
Ki 0.05Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes [AID304392, Type: Literature]Adenosine receptor A [gi:1351831]
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2
[SID103540614]
Ki 0.05Displacement of [125I]ABMECA from human adenosine A3 receptor expressed in CHO cell membranes [AID304392, Type: Literature]Adenosine receptor A [gi:1351831]
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3
[SID103540614]
IC50 0.238Activity at human adenosine A3 receptor expressed in CHO cells assessed as antagonism of Cl-IB-MECA-inhibited cAMP production [AID304396, Type: Literature]Adenosine receptor A [gi:1351831]
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4
[SID103540614]
IC50 0.238Activity at human adenosine A3 receptor expressed in CHO cells assessed as antagonism of Cl-IB-MECA-inhibited cAMP production [AID304396, Type: Literature]Adenosine receptor A [gi:1351831]
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5
[SID103540614]
 Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes at 1 uM [AID304393, Type: Literature]Adenosine receptor A [gi:231473]
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6
[SID103540614]
 Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes at 1 uM [AID304393, Type: Literature]Adenosine receptor A [gi:231473]
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7
[SID103540614]
 Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes at 1 uM [AID304393, Type: Literature]Adenosine receptor A [gi:231473]
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8
[SID103540614]
 Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in CHO cell membranes at 1 uM [AID304394, Type: Literature]Adenosine receptor A2 [gi:543740]
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9
[SID103540614]
 Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in CHO cell membranes at 1 uM [AID304394, Type: Literature]Adenosine receptor A2 [gi:543740]
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10
[SID103540614]
 Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in CHO cell membranes at 1 uM [AID304394, Type: Literature]Adenosine receptor A2 [gi:543740]
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11
[SID103540614]
 Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated cAMP levels at 1 uM [AID304395, Type: Literature]Adenosine receptor A2 [gi:112938]
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