| 1 | [SID103716704] | Active | IC50 | 0.011 | Inhibition of rat soluble epoxide hydrolase [AID484178, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:462371] |   View X | Row No. | 1 | | Structure | 
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.011 [uM] | | BioAssay | Inhibition of rat soluble epoxide hydrolase | | AID | 484178 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:462371] | | PubMed | 20472432 | | Data Table | |
|
| 2 | [SID103716704] | Active | IC50 | 0.015 | Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA [AID453481, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:67476665] | View X | Row No. | 2 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.015 [uM] | | BioAssay | Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA | | AID | 453481 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:67476665] | | PubMed | 19969453 | | Data Table | |
|
| 3 | [SID103716704] | Active | IC50 | 0.015 | Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA [AID453481, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:67476665] | View X | Row No. | 3 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.015 [uM] | | BioAssay | Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid after 30 mins by ELISA | | AID | 453481 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:67476665] | | PubMed | 19969453 | | Data Table | |
|
| 4 | [SID103716704] | Active | IC50 | 0.015 | Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assay [AID453480, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:67476665] | View X | Row No. | 4 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.015 [uM] | | BioAssay | Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assay | | AID | 453480 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:67476665] | | PubMed | 19969453 | | Data Table | |
|
| 5 | [SID103716704] | Active | IC50 | 0.015 | Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assay [AID453480, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:67476665] | View X | Row No. | 5 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.015 [uM] | | BioAssay | Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assay | | AID | 453480 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:67476665] | | PubMed | 19969453 | | Data Table | |
|
| 6 | [SID103716704] | Active | IC50 | 0.015 | Inhibition of human sEH by cell based assay [AID676945, Type: Literature] | | View X | Row No. | 6 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.015 [uM] | | BioAssay | Inhibition of human sEH by cell based assay | | AID | 676945 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 7 | [SID103716704] | Active | IC50 | 0.015 | Inhibition of human sEH [AID676944, Type: Literature] | | View X | Row No. | 7 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.015 [uM] | | BioAssay | Inhibition of human sEH | | AID | 676944 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 8 | [SID103716704] | Active | IC50 | 0.018 | Inhibition of human soluble epoxide hydrolase [AID484177, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:67476665] | View X | Row No. | 8 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.018 [uM] | | BioAssay | Inhibition of human soluble epoxide hydrolase | | AID | 484177 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:67476665] | | PubMed | 20472432 | | Data Table | |
|
| 9 | [SID103716704] | Active | IC50 | 0.018 | Inhibition of human soluble epoxide hydrolase [AID484177, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:67476665] | View X | Row No. | 9 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.018 [uM] | | BioAssay | Inhibition of human soluble epoxide hydrolase | | AID | 484177 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:67476665] | | PubMed | 20472432 | | Data Table | |
|
| 10 | [SID103716704] | Active | IC50 | 0.063 | Inhibition of human soluble epoxide hydrolase assessed as [2-3H]trans-1,3-diphenyl propylene oxide hydrolysis by cellular assay [AID484176, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:67476665] | View X | Row No. | 10 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.063 [uM] | | BioAssay | Inhibition of human soluble epoxide hydrolase assessed as [2-3H]trans-1,3-diphenyl propylene oxide hydrolysis by cellular assay | | AID | 484176 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:67476665] | | PubMed | 20472432 | | Data Table | |
|
| 11 | [SID103716704] | Active | IC50 | 0.063 | Inhibition of human soluble epoxide hydrolase assessed as [2-3H]trans-1,3-diphenyl propylene oxide hydrolysis by cellular assay [AID484176, Type: Literature] | Bifunctional epoxide hydrolase 2 [gi:67476665] | View X | Row No. | 11 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 0.063 [uM] | | BioAssay | Inhibition of human soluble epoxide hydrolase assessed as [2-3H]trans-1,3-diphenyl propylene oxide hydrolysis by cellular assay | | AID | 484176 | | BioAssay type | Literature | | Target | Bifunctional epoxide hydrolase 2 [gi:67476665] | | PubMed | 20472432 | | Data Table | |
|
| 12 | [SID103716704] | Active | IC50 | 19 | Inhibition of CYP2C19 [AID676948, Type: Literature] | | View X | Row No. | 12 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 19 [uM] | | BioAssay | Inhibition of CYP2C19 | | AID | 676948 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 13 | [SID103716704] | Active | IC50 | 19 | Inhibition of CYP2C19 [AID453484, Type: Literature] | | View X | Row No. | 13 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 19 [uM] | | BioAssay | Inhibition of CYP2C19 | | AID | 453484 | | BioAssay type | Literature | | Target | | | PubMed | 19969453 | | Data Table | |
|
| 14 | [SID103716704] | Active | IC50 | 20 | Inhibition of CYP2C9 [AID453483, Type: Literature] | | View X | Row No. | 14 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 20 [uM] | | BioAssay | Inhibition of CYP2C9 | | AID | 453483 | | BioAssay type | Literature | | Target | | | PubMed | 19969453 | | Data Table | |
|
| 15 | [SID103716704] | Active | IC50 | 20 | Inhibition of CYP2J2 [AID453482, Type: Literature] | | View X | Row No. | 15 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 20 [uM] | | BioAssay | Inhibition of CYP2J2 | | AID | 453482 | | BioAssay type | Literature | | Target | | | PubMed | 19969453 | | Data Table | |
|
| 16 | [SID103716704] | Active | IC50 | 20 | Inhibition of CYP2J2 [AID484179, Type: Literature] | | View X | Row No. | 16 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 20 [uM] | | BioAssay | Inhibition of CYP2J2 | | AID | 484179 | | BioAssay type | Literature | | Target | | | PubMed | 20472432 | | Data Table | |
|
| 17 | [SID103716704] | Active | IC50 | 20 | Inhibition of CYP2J2 [AID676946, Type: Literature] | | View X | Row No. | 17 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 20 [uM] | | BioAssay | Inhibition of CYP2J2 | | AID | 676946 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 18 | [SID103716704] | Active | IC50 | 20 | Inhibition of CYP2C9 [AID676947, Type: Literature] | | View X | Row No. | 18 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 20 [uM] | | BioAssay | Inhibition of CYP2C9 | | AID | 676947 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 19 | [SID103716704] | Active | IC50 | 25.5 | Inhibition of CYP2C9 [AID484180, Type: Literature] | | View X | Row No. | 19 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | IC50 | 25.5 [uM] | | BioAssay | Inhibition of CYP2C9 | | AID | 484180 | | BioAssay type | Literature | | Target | | | PubMed | 20472432 | | Data Table | |
|
| 20 | [SID103716704] | Active | | | Plasma concentration in Sprague-Dawley rat at 5 mg/kg, po after 4 hrs by LC-MS/MS analysis [AID453488, Type: Literature] | | View X | Row No. | 20 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | BioAssay | Plasma concentration in Sprague-Dawley rat at 5 mg/kg, po after 4 hrs by LC-MS/MS analysis | | AID | 453488 | | BioAssay type | Literature | | Target | | | PubMed | 19969453 | | Data Table | |
|
| 21 | [SID103716704] | Active | | | Plasma concentration in rat at 5 mg/kg, po after 4 hrs [AID676952, Type: Literature] | | View X | Row No. | 21 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Active | | BioAssay | Plasma concentration in rat at 5 mg/kg, po after 4 hrs | | AID | 676952 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 22 | [SID103716704] | Unspecified | | | Half life in human liver microsomes after 30 mins by LC-MS/MS analysis in presence of NADPH [AID453485, Type: Literature] | | View X | Row No. | 22 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Unspecified | | BioAssay | Half life in human liver microsomes after 30 mins by LC-MS/MS analysis in presence of NADPH | | AID | 453485 | | BioAssay type | Literature | | Target | | | PubMed | 19969453 | | Data Table | |
|
| 23 | [SID103716704] | Unspecified | | | Half life in rat liver microsomes after 30 mins by LC-MS/MS analysis in presence of NADPH [AID453486, Type: Literature] | | View X | Row No. | 23 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Unspecified | | BioAssay | Half life in rat liver microsomes after 30 mins by LC-MS/MS analysis in presence of NADPH | | AID | 453486 | | BioAssay type | Literature | | Target | | | PubMed | 19969453 | | Data Table | |
|
| 24 | [SID103716704] | Unspecified | | | Solubility of the compound [AID453487, Type: Literature] | | View X | Row No. | 24 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Unspecified | | BioAssay | Solubility of the compound | | AID | 453487 | | BioAssay type | Literature | | Target | | | PubMed | 19969453 | | Data Table | |
|
| 25 | [SID103716704] | Unspecified | | | Half life in human liver microsomes [AID676949, Type: Literature] | | View X | Row No. | 25 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Unspecified | | BioAssay | Half life in human liver microsomes | | AID | 676949 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 26 | [SID103716704] | Unspecified | | | Half life in rat liver microsomes [AID676950, Type: Literature] | | View X | Row No. | 26 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Unspecified | | BioAssay | Half life in rat liver microsomes | | AID | 676950 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 27 | [SID103716704] | Unspecified | | | Solubility of the compound [AID676951, Type: Literature] | | View X | Row No. | 27 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Unspecified | | BioAssay | Solubility of the compound | | AID | 676951 | | BioAssay type | Literature | | Target | | | PubMed | 22168898 | | Data Table | |
|
| 28 | [SID103716704] | Unspecified | | | Half life in human liver microsome [AID484181, Type: Literature] | | View X | Row No. | 28 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Unspecified | | BioAssay | Half life in human liver microsome | | AID | 484181 | | BioAssay type | Literature | | Target | | | PubMed | 20472432 | | Data Table | |
|
| 29 | [SID103716704] | Unspecified | | | Half life in mouse liver microsome [AID484182, Type: Literature] | | View X | Row No. | 29 | | Structure |
| | Substance | | | SID | 103716704 | | CID | 24748513 | | Outcome | Unspecified | | BioAssay | Half life in mouse liver microsome | | AID | 484182 | | BioAssay type | Literature | | Target | | | PubMed | 20472432 | | Data Table | |
|
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
