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AGN-PC-04PB9E (CID 24687847) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(460)
 
 
Inconclusive(6)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(15)
 
 
CAP ED(5)
 
 
TRP 2(5)
 
 
NR LBD Lrh-1(4)
 
 
 
BioAssay Types:
Screening(348)
 
 
 
Confirmatory(122)
 
 
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(101)
 
 
 
 
IC50(19)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 440    Data Row: 476   Total Pages: 24   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID160644488]
IC50 1.372Late stage luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651976, Type: confirmatory]nuclear receptor subfamily 5 group A member 2 isoform 2 [Homo sapiens] [gi:4504343]
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2
[SID56321798]
IC50 3.092Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1) [AID651968, Type: confirmatory]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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3
[SID56321798]
IC50 3.117Luminescence-based cell-based high throughput dose response assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651970, Type: confirmatory]nuclear receptor subfamily 5 group A member 2 isoform 2 [Homo sapiens] [gi:4504343]
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4
[SID160644488]
IC50 3.553Late stage counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1) [AID651977, Type: confirmatory]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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5
[SID56321798]
uHTS luminescence assay for the identification of chemical inhibitors of B-cell specific antigen receptor-induced NF-kB activation [AID435022, Type: screening]
View
6
[SID56321798]
Counterscreen for PME1 inhibitors: fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of lysophospholipase 2 (LYPLA2). [AID2177, Type: screening]lysophospholipase II [Homo sapiens] [gi:4581413]
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7
[SID56321798]
Counterscreen for PME1 inhibitors: fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of lysophospholipase 2 (LYPLA2). [AID2232, Type: screening]lysophospholipase II [Homo sapiens] [gi:4581413]
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8
[SID56321798]
Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1) [AID651614, Type: screening]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
View
9
[SID56321798]
Luminescence-based cell-based high throughput confirmation assay for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID651613, Type: screening]nuclear receptor subfamily 5 group A member 2 isoform 2 [Homo sapiens] [gi:4504343]
View
10
[SID56321798]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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11
[SID56321798]
IC50 35.871Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify nonselective inhibitors of the Steroidogenic acute regulatory protein (StAR) promoter or luminescence assay artifacts [AID651969, Type: confirmatory]
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12
[SID160644488]
IC50 35.871Late stage counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify nonselective inhibitors of the Steroidogenic acute regulatory protein (StAR) promoter or luminescence assay artifacts [AID651975, Type: confirmatory]
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13
[SID56321798]
IC50 35.871Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID651973, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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14
[SID160644488]
IC50 35.871Late stage counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) [AID651974, Type: confirmatory]transactivating tegument protein VP16 [Human herpesvirus 1] [gi:9629429]
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15
[SID56321798]
Potency 84.9214qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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16
[SID56321798]
ARNT-TAC3: AlphaScreen HTS to detect disruption of ARNT/TAC3 interactions Measured in Biochemical System Using Plate Reader - 2158-01_Inhibitor_SinglePoint_HTS_Activity [AID623870, Type: screening]transforming acidic coiled-coil-containing protein 3 [Homo sapiens] [gi:5454102]
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17
[SID56321798]
Potency qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101 [AID493005, Type: confirmatory]tumor susceptibility gene 101 protein [Homo sapiens] [gi:5454140]
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18
[SID56321798]
Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of the Steroid Receptor Coactivator 2 (SRC2; NCOA2) [AID651957, Type: screening]nuclear receptor coactivator 2 [Homo sapiens] [gi:5729858]
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19
[SID56321798]
Potency qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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20
[SID56321798]
uHTS identification of CXCR6 Inhibitors in a B-arrestin luminescence assay [AID602244, Type: screening]C-X-C chemokine receptor type 6 [Homo sapiens] [gi:5730106]
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