hydrazoic acid (CID 24530) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(8)
 
 
Inconclusive(1)
 
 
Unspecified(11)
 
 
Top Targets:
alpha CA I II..(8)
 
 
 
alpha CA IV X..(2)
 
 
 
LbH gamma CA(1)
 
 
alpha CA(1)
 
 
alpha CA VI(1)
 
 
BioAssay Types:
Literature(20)
 
 
 
 
BioActivity Types:
Ki(18)
 
 
 
IC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 20    Data Row: 20   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103452224]
Ki 1.2e-06Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli [AID238687, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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2
[SID103452224]
Ki 0.0003Inhibitory activity against human carbonic anhydrase V expressed in Escherichia coli [AID238688, Type: Literature]
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3
[SID103452224]
Ki 0.0015Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli [AID238715, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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4
[SID103452224]
Ki 0.0048Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10 [AID238853, Type: Literature]
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5
[SID103452224]
Ki 1.2Inhibitory constant against carbonic anhydrase I [AID238317, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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6
[SID103452224]
Ki 1.2Inhibition constant of anion against human carbonic anhydrase isozyme hCA I [AID238513, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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7
[SID103452224]
Ki 1.2Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assay [AID552127, Type: Literature]Carbonic anhydrase 1 [gi:115449]
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8
[SID103452224]
Ki 5Inhibition constant of anion against human carbonic anhydrase isozyme hCA IX [AID238546, Type: Literature]Carbonic anhydrase 9 [gi:83300925]
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9
[SID103452224]
Ki 70Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assay [AID552129, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
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10
[SID103452224]
Ki 300Inhibition constant of anion against human carbonic anhydrase isozyme hCA V [AID238515, Type: Literature]
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11
[SID103452224]
Ki 520Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay [AID552130, Type: Literature]
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12
[SID103452224]
Ki 1500Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assay [AID552128, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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13
[SID103452224]
Ki 1500Inhibitory constant against carbonic anhydrase II [AID238327, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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14
[SID103452224]
Ki 1500Inhibition constant of anion against human carbonic anhydrase isozyme hCA II [AID238542, Type: Literature]Carbonic anhydrase 2 [gi:115456]
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15
[SID103452224]
IC50 3000Inhibition of bacterial SecA ATPase [AID457591, Type: Literature]
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16
[SID103452224]
Ki 4680Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay [AID552131, Type: Literature]
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17
[SID103452224]
Ki 5800Inhibitory constant against Zn-Cam (Methanosarcina thermophila) [AID238607, Type: Literature]Carbonic anhydrase [gi:729004]
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18
[SID103452224]
Ki 55700Inhibitory constant against methanoarchaeon Methanobacterium thermoautotrophicum (Cab) [AID238958, Type: Literature]
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19
[SID103452224]
Ki 65100Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV [AID238544, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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20
[SID103452224]
 Inhibitory constant against carbonic anhydrase IV ; nt= not tested [AID238653, Type: Literature]Carbonic anhydrase 4 [gi:115465]
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