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bronopol (CID 2450) - Compound BioActivity Data
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BioActivity Outcomes:
Active(26)
 
 
Inactive(209)
 
 
Inconclusive(52)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD ER(16)
 
 
 
NR LBD AR(16)
 
 
 
 
NR LBD PPAR(15)
 
 
 
NR LBD GR(10)
 
 
 
NR LBD TR(10)
 
 
 
 
BioAssay Types:
Confirmatory(175)
 
 
 
 
Literature(62)
 
 
 
 
Summary(39)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(203)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 158    Data Row: 289   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26757474]
Potency 1.7783qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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2
[SID144205632]
Potency 4.2172qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID144205632]
Potency 4.7318qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID26757474]
Potency 5.6234Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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5
[SID144210446]
Potency-Replicate_1 6.1131qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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6
[SID144210446]
Potency-Replicate_1 7.6959qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID144205632]
Potency-Replicate_1 8.4127qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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8
[SID26757474]
Potency 8.9125qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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9
[SID26757474]
Potency 8.9125qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase: hit validation [AID492961, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:72386991]
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10
[SID26757474]
Potency 10qHTS of Trypanosoma Brucei Inhibitors [AID624173, Type: confirmatory]hypothetical protein, conserved [Trypanosoma brucei] [gi:62359610]
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11
[SID144210446]
Ratio Potency (uM) 12.1972qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID144210446]
Potency-Replicate_1 12.1972qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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13
[SID144205632]
Potency-Replicate_1 18.8336qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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14
[SID144210446]
Potency-Replicate_1 21.6899qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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15
[SID144205632]
Potency-Replicate_1 23.7101qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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16
[SID144205632]
Potency-Replicate_1 23.7101qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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17
[SID144210446]
Potency-Replicate_1 24.3365qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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18
[SID144205632]
Potency-Replicate_1 26.6032qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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19
[SID26757474]
Potency 28.6954S16 Schwann cell viability assay (CellTiter-Glo assay) [AID624031, Type: confirmatory]
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20
[SID144205632]
Potency 50.1187qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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