Bookmark and Share
Benzoic Acid (CID 243) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(34)
 
 
Inactive(716)
 
 
Inconclusive(15)
 
 
Unspecified(396)
 
 
Top Targets:
7tm 4(58)
 
 
 
NR LBD PPAR(21)
 
 
 
NR LBD ER(18)
 
 
 
 
 
NR LBD AR(17)
 
 
 
 
p450(14)
 
 
 
BioAssay Types:
Confirmatory(485)
 
 
 
 
 
Screening(262)
 
 
 
Literature(187)
 
 
 
 
Summary(48)
 
 
 
BioActivity Types:
Potency(360)
 
 
 
 
 
IC50(136)
 
 
 
 
Ki(14)
 
 
 
Kd(3)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1017    Data Row: 1161   Total Pages: 59   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176121]
IC50 0.2Antihemorrhagic activity in ddY mouse assessed as inhibition of Protobothrops flavoviridis venom-induced hemorrhagic lesion formation compound incubated with venom for 10 mins and administered subcutaneously measured after 24 hrs [AID631927, Type: Literature]
View
2
[SID103176121]
Ki 2Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine [AID745647, Type: Literature]D-amino-acid oxidase [gi:25453448]
View
3
[SID103176121]
IC50 2.0893Competitive inhibition of human recombinant DAAO after 1 hr by coupled enzyme assay in presence of D-serine [AID745648, Type: Literature]D-amino-acid oxidase [gi:25453448]
View
4
[SID103176121]
Kd 2.2Binding affinity to human recombinant DAAO at 492 nm spectral modification by spectrophotometric analysis in presence of FAD [AID745628, Type: Literature]D-amino-acid oxidase [gi:25453448]
View
5
[SID103176121]
Kd 2.3Binding affinity to human recombinant DAAO by stopped flow spectrophotometric analysis in presence of FAD [AID745649, Type: Literature]D-amino-acid oxidase [gi:25453448]
View
6
[SID144209601]
Potency-Replicate_1 5.0987qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
7
[SID103176121]
Ki 7Inhibition of human recombinant DAO expressed in Escherichia coli BL21(DE3) by oxygraphic assay [AID726204, Type: Literature]D-amino-acid oxidase [gi:25453448]
View
8
[SID103176121]
Kd 9Binding affinity to human recombinant DAAO at 442 nm spectral modification by spectrophotometric analysis in presence of FAD [AID745651, Type: Literature]D-amino-acid oxidase [gi:25453448]
View
9
[SID103176121]
Ki 10.9Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot analysis [AID726213, Type: Literature]D-amino-acid oxidase [gi:25453448]
View
10
[SID103176121]
Ki 13.8038Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
View
11
[SID103176121]
Ki 37.5Inhibition of human recombinant N-terminal His-tagged DAO Y224A mutant expressed in Escherichia coli BL21(DE3) using D-alanine as substrate after 10 mins by Lineweaver-Burk plot analysis [AID726214, Type: Literature]
View
12
[SID103176121]
IC50 46.9Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by colorimetric assay [AID726222, Type: Literature]D-amino-acid oxidase [gi:25453448]
View
13
[SID46392378]
Ki 100Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Structure Of Nitroreductase From E. Cloacae Complex With Inhibitor Benzoate [gi:20150964]
View
14
[SID46392378]
Ki 100Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Structure Of Nitroreductase From E. Cloacae Complex With Inhibitor Benzoate [gi:20150964]
View
15
[SID46392378]
Ki 100Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, Structure Of Nitroreductase From E. Cloacae Complex With Inhibitor Benzoate [gi:20150965]
View
16
[SID46392378]
Ki 100Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, Structure Of Nitroreductase From E. Cloacae Complex With Inhibitor Benzoate [gi:20150965]
View
17
[SID46392055]
Ki 3300Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, The Crystal Structure Of Ydce, A 4-Oxalocrotonate Tautomerase Homologue From Escherichia Coli, Confirms The Structural Basis For Oligomer Diversity [gi:24987272]
View
18
[SID46392055]
Ki 3300Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain B, The Crystal Structure Of Ydce, A 4-Oxalocrotonate Tautomerase Homologue From Escherichia Coli, Confirms The Structural Basis For Oligomer Diversity [gi:24987273]
View
19
[SID46392055]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: other]Chain A, The Crystal Structure Of Ydce, A 4-Oxalocrotonate Tautomerase Homologue From Escherichia Coli, Confirms The Structural Basis For Oligomer Diversity [gi:24987272]
View
20
[SID103176121]
Competitive inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-alanine as substrate by Lineweaver-Burk plot analysis [AID726216, Type: Literature]D-amino-acid oxidase [gi:25453448]
View