Bookmark and Share
2-(2,3-Dihydro-1H-8-thia-5,7-diaza-cyclopenta[a]inden-4-ylsulfanyl)-benzoic acid (CID 2415319) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(24)
 
 
Inactive(685)
 
 
Inconclusive(7)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(43)
 
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
Lactamase B(9)
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(476)
 
 
 
 
Confirmatory(217)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(148)
 
 
 
 
 
IC50(46)
 
 
 
EC50(17)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 652    Data Row: 717   Total Pages: 36   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24834296]
EC50_MICROM 1.078Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant [AID1339, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
View
2
[SID24834296]
EC50_MICROM 1.219Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID1340, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
View
3
[SID24834296]
EC50_MICROM 1.837Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant [AID1333, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
View
4
[SID24834296]
EC50_MICROM 2.624Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID1336, Type: confirmatory]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
View
5
[SID24834296]
EC50_MICROM 2.762Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID1337, Type: confirmatory]Ras-related protein Rab-2A [gi:46577642]
View
6
[SID24834296]
IC50 3.91FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. [AID1926, Type: confirmatory]metallo beta-lactamase [Pseudomonas aeruginosa] [gi:7381449]
View
7
[SID24834296]
EC50_MICROM 4.375Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID1334, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
View
8
[SID24834296]
IC50 7.047TRFRET-based cell-based high throughput dose response assay to identify inhibitors of cell surface Prion Protein (PRPC) [AID743453, Type: confirmatory]major prion protein preproprotein [Homo sapiens] [gi:4506113]
View
9
[SID24834296]
Potency 8.9125qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase [gi:44888968]
View
10
[SID24834296]
Potency 10qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]neuropeptide S receptor isoform A [Homo sapiens] [gi:46395496]
View
11
[SID24834296]
Potency 15.8489qHTS Assay for Agonists of the Relaxin Receptor RXFP1 [AID2676, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
View
12
[SID24834296]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID761, Type: screening]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
View
13
[SID24834296]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID757, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
View
14
[SID24834296]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant [AID764, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
View
15
[SID24834296]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID760, Type: screening]Ras-related protein Rab-2A [gi:46577642]
View
16
[SID24834296]
Primary biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase [AID1527, Type: screening]metallo beta-lactamase [Pseudomonas aeruginosa] [gi:7381449]
View
17
[SID24834296]
FRET-based counterscreen assay for selective VIM-2 inhibitors: biochemical high throughput screening assay to identify epi-absorbance assay artifacts [AID1857, Type: screening]metallo beta-lactamase [Pseudomonas aeruginosa] [gi:7381449]
View
18
[SID24834296]
Epi-absorbance-based confirmation assay for common VIM-2 and IMP-1 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase. [AID2187, Type: screening]metallo beta-lactamase [Pseudomonas aeruginosa] [gi:7381449]
View
19
[SID24834296]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
View
20
[SID24834296]
TRFRET-based cell-based primary high throughput screening assay to identify inhibitors of cell surface Prion Protein (PRPC) [AID720596, Type: screening]major prion protein preproprotein [Homo sapiens] [gi:4506113]
View