Acetylglucosamine (CID 24139) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(4)
 
 
Inactive(12)
 
 
Inconclusive(23)
 
 
Unspecified(47)
 
 
Top Targets:
23DHB-AMP lg(1)
 
 
Chorismate bi..(1)
 
 
DNA pol B 3(1)
 
 
DUF3346(1)
 
 
Ggt(1)
 
 
BioAssay Types:
Literature(43)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
IC50(8)
 
 
 
Ki(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 86    Data Row: 86   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103583176]
IC50 1.99526Binding affinity to fluorescein-labeled rat NKR-P1A after 2 hrs by fluorescence assay [AID489738, Type: Literature]
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2
[SID103583176]
IC50 2.51189Activation of rat NKR-P1A [AID493446, Type: Literature]
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3
[SID103583176]
IC50 23Inhibition of binding of HRP labeled WGA to immobilized N-acetyl-glucosamine [AID302091, Type: Literature]
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4
[SID103583176]
 Activity of Escherichia coli O55:H7 glycosyltransferase WbgO [AID450450, Type: Literature]
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5
[SID103583176]
IC50 125.893Binding affinity to rhodamine-labeled human CD69 receptor after 2 hrs by fluorescence assay [AID489739, Type: Literature]
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6
[SID103583176]
IC50 316.228Activation of human CD69 [AID493447, Type: Literature]
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7
[SID103583176]
Km 323Activity of Escherichia coli O55:H7 glycosyltransferase WbgO by Lineweaver-Burke analysis [AID450448, Type: Literature]
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8
[SID103583176]
Ki 540Kinetic data for inhibition of Beta-1,4-GalT by polymer-supported Nacetylglucosamine. [AID220917, Type: Literature]
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9
[SID103583176]
IC50 1000Inhibition of human rhodamine-labelled soluble CD69 by standard plate inhibition assay [AID459221, Type: Literature]
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10
[SID103583176]
Km 10500Kinetic data for inhibition of Beta-1,4-GalT by polymer-supported Nacetylglucosamine. [AID220919, Type: Literature]
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11
[SID103583176]
Ki 14300Kinetic data for inhibition of Beta-1,4-GalT by free N-acetyl-glucosamine [AID220916, Type: Literature]
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12
[SID103583176]
Km 34600Kinetic data for inhibition of Beta-1,4-GalT by free N-acetyl-glucosamine [AID220918, Type: Literature]
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13
[SID103583176]
MIC 50000Anticryptosporidial activity against Cryptosporidium parvum GCH1 assessed as inhibition of rabbit erythrocytes hemagglutination [AID381592, Type: Literature]
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14
[SID103583176]
MIC 100000Anticryptosporidial activity against Cryptosporidium hominis TU502 assessed as inhibition of rabbit erythrocytes hemagglutination [AID381594, Type: Literature]
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15
[SID103583176]
IC50 500000Inhibition of Cryptosporidium parvum recombinant Galactose/N-acetylgalactosamine-specific lectin binding to Caco2A cells [AID381596, Type: Literature]
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16
[SID103583176]
IC50 1e+06Inhibition of binding of HRP labeled WGA to immobilized porcine stomach mucine [AID302089, Type: Literature]
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17
[SID103583176]
 Inhibition of binding of HRP labeled WGA to immobilized porcine stomach mucine relative to N-acetyl-glucosamine [AID302090, Type: Literature]
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18
[SID103583176]
 Anticryptosporidial activity against Cryptosporidium parvum GCH1 assessed as inhibition of rabbit erythrocytes hemagglutination relative to galactose [AID381593, Type: Literature]
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19
[SID103583176]
 Anticryptosporidial activity against Cryptosporidium hominis TU502 assessed as inhibition of rabbit erythrocytes hemagglutination relative to galactose [AID381595, Type: Literature]
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20
[SID103583176]
 Acceptor substrate specificity toward Fucosyltransferase for the galactosides of GlcNAc with beta 1,3 or beta 1,4-linkages [AID71968, Type: other]
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21
[SID103583176]
 Ratio of Kcat to Km for Escherichia coli O55:H7 glycosyltransferase WbgO by Lineweaver-Burke analysis [AID450449, Type: Literature]
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22
[SID103583176]
 Chondroprotective activity in bovine articular cartilage explant cultures assessed as reduction in IL1-induced glycosaminoglycan release at 1 mM after 96 hrs [AID362960, Type: Literature]
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23
[SID103583176]
 Cytotoxicity against bovine chondrocytes at 10 mM after 96 hrs by MTT cell viability assay [AID362961, Type: Literature]
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24
[SID103583176]
 Chondroprotective activity in bovine articular cartilage explant cultures assessed as reduction in IL1-induced glycosaminoglycan release at 10 mM after 96 hrs relative to control [AID362962, Type: Literature]
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25
[SID103583176]
 Chondroprotective activity in bovine articular cartilage explant cultures assessed as reduction in IL1-induced glycosaminoglycan release at 10 mM after 96 hrs [AID362963, Type: Literature]
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26
[SID103583176]
 Chondroprotective activity in bovine articular cartilage explant cultures assessed as reduction in IL1-induced glycosaminoglycan release at 1 mM after 96 hrs relative to control [AID362964, Type: Literature]
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27
[SID103583176]
 Cytotoxicity against bovine chondrocytes at 1 mM after 96 hrs by MTT cell viability assay [AID362965, Type: Literature]
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28
[SID103583176]
 Chondroprotective activity in bovine articular cartilage explant cultures assessed as reduction in IL1-induced glycosaminoglycan release at 0.1 mM after 96 hrs [AID362966, Type: Literature]
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29
[SID103583176]
 Chondroprotective activity in bovine articular cartilage explant cultures assessed as reduction in IL1-induced glycosaminoglycan release at 0.1 mM after 96 hrs relative to control [AID362967, Type: Literature]
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30
[SID103583176]
 Cytotoxicity against bovine chondrocytes at 0.1 mM after 96 hrs by MTT cell viability assay [AID362968, Type: Literature]
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31
[SID103583176]
 Inhibition of Cryptosporidium parvum recombinant Galactose/N-acetylgalactosamine-specific lectin binding to Caco2A cells relative to galactose [AID381597, Type: Literature]
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32
[SID103583176]
 Kinetic data for inhibition of Beta-1,4-GalT by free N-acetyl-glucosamine [AID220920, Type: Literature]
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33
[SID103583176]
 Kinetic data for inhibition of Beta-1,4-GalT by polymer-supported Nacetylglucosamine. [AID220921, Type: Literature]
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34
[SID8149651]
 Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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35
[SID8149651]
 Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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36
[SID8149651]
 Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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37
[SID8149651]
 Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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38
[SID8149651]
 Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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39
[SID8149651]
 Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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40
[SID8149651]
 Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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41
[SID8149651]
 Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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42
[SID8149651]
 Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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43
[SID8149651]
 Screen for compounds that correct neuronal dysfunction without cell death as induced by the expression of polyglutamine-expanded, N-terminal huntingtin in C. elegans mechanosensory neurons (HDELENEU) [AID1599, Type: other]
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44
[SID103583176]
 Activity of Escherichia coli O55:H7 glycosyltransferase WbgO relative to GlcNAc [AID450447, Type: Literature]
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45
[SID103583176]
 Antimycobacterial activity against Mycobacterium tuberculosis H37Rv [AID569255, Type: Literature]
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46
[SID103583176]
 Antimycobacterial activity against Mycobacterium bovis BCG str. Tokyo 172 [AID569256, Type: Literature]
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47
[SID103583176]
 Antimycobacterial activity against Mycobacterium avium subsp. hominissuis 104 [AID569258, Type: Literature]
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48
[SID103583176]
 Antimycobacterial activity against Mycobacterium avium subsp. avium ATCC 2529I [AID569259, Type: Literature]
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49
[SID103583176]
 Antimicrobial activity against Staphylococcus aureus [AID569260, Type: Literature]
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50
[SID103583176]
 Antimicrobial activity against methicilin-resistant Staphylococcus aureus 873 [AID569261, Type: Literature]
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