Benzene (CID 241) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(11)
 
 
Inactive(357)
 
 
Inconclusive(13)
 
 
Unspecified(27)
 
 
Top Targets:
NR LBD PPAR(20)
 
 
 
NR LBD TR(16)
 
 
P53(8)
 
 
 
NR LBD VDR(8)
 
 
NR LBD RXR li..(8)
 
 
 
BioAssay Types:
Confirmatory(334)
 
 
 
Literature(31)
 
 
 
 
BioActivity Types:
Potency(262)
 
 
 
Kd(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 174    Data Row: 408   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48413264]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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2
[SID48413264]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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3
[SID48413264]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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4
[SID48414934]
 DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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5
[SID48413264]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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6
[SID46392176]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Hiv Integrase Core Domain Complexed With A Derivative Of Tetraphenyl Arsonium. [gi:13786709]
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7
[SID53813070]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Complex Structure Of Sars-Cov 3c-Like Protease With Pma [gi:163931116]
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8
[SID46392408]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, A Cavity-Containing Mutant Of T4 Lysozyme Is Stabilized By Buried Benzene [gi:157831738]
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9
[SID46393762]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Generating Ligand Binding Sites In T4 Lysozyme Using Deficiency-Creating Substitutions [gi:157834474]
View
10
[SID46393763]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Generating Ligand Binding Sites In T4 Lysozyme Using Deficiency-Creating Substitutions [gi:157834478]
View
11
[SID46393179]
 Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Gcn4-Leucine Zipper Core Mutant As N16a Complexed With Benzene [gi:157880156]
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12
[SID103179304]
Kd 175Dissociation constant against T4 lysozyme mutant L99A [AID238119, Type: Literature]Lysozyme [gi:126605]
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13
[SID26757302]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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14
[SID26757303]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
15
[SID103179304]
 Aqueous solubility [AID19262, Type: Literature]
View
16
[SID103179304]
 logD (measured by HPLC) (as log k') [AID23960, Type: Literature]
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17
[SID103179304]
 logD (measured by HPLC) (as log k') [AID23961, Type: Literature]
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18
[SID103179304]
 logD (measured by HPLC) (as log k') [AID23963, Type: Literature]
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19
[SID103179304]
 logD (measured by HPLC) (as log k') [AID23965, Type: Literature]
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20
[SID103179304]
 logD (measured by HPLC) (as log k') [AID23968, Type: Literature]
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21
[SID103179304]
 logD (measured by HPLC) (as log k') [AID23970, Type: Literature]
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22
[SID103179304]
 logD (measured by HPLC) (as log k') [AID23971, Type: Literature]
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23
[SID103179304]
 Partition coefficient (logD, measured by HPLC, log k') [AID23973, Type: Literature]
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24
[SID103179304]
 Partition coefficient (logP) [AID24226, Type: Literature]
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25
[SID103179304]
 logBB, log(C brain / C blood) [AID26047, Type: Literature]
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26
[SID103179304]
 Partition coefficient (logD7.4) [AID26296, Type: Literature]
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27
[SID103179304]
 Toxicity determined using Golden Orfe Fish Test [AID101345, Type: Literature]
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28
[SID103179304]
 Toxicity determined using Microtox Test [AID159270, Type: Literature]
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29
[SID103179304]
 The toxicity of compound was determined using Konemann's Industrial Pollutants Toxicity Test [AID162230, Type: Literature]
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30
[SID103179304]
 Toxicity determined using Tadpole Narcosis Test [AID212400, Type: Literature]
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31
[SID103179304]
 Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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32
[SID103179304]
 Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
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33
[SID103179304]
 In-vitro air to lung partition coefficients of the compound, logK(lung) (human/rat) [AID603950, Type: Literature]
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34
[SID103179304]
 In-vitro air to blood partition coefficients of the compound, logK(blood) (human/rat) [AID603951, Type: Literature]
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35
[SID103179304]
 In-vitro blood to lung partition coefficients of the compound, logP(lung) (human/rat) [AID603952, Type: Literature]
View
36
[SID103179304]
 Octanol-water partition coefficient, log P of the compound [AID603957, Type: Literature]
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37
[SID17389168]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
38
[SID17390025]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
39
[SID17389168]
Potency 7.9433qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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40
[SID17389168]
Potency 7.9433qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
41
[SID17389168]
Potency 7.9433qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
42
[SID26757303]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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43
[SID26757303]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
44
[SID26757303]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
45
[SID26757303]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
46
[SID26757303]
Potency qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
47
[SID26757303]
Potency qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
48
[SID26757303]
Potency qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
49
[SID26757303]
Potency qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
50
[SID26757302]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View