Bookmark and Share
Benzene (CID 241) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(12)
 
 
Inactive(463)
 
 
Inconclusive(22)
 
 
Unspecified(32)
 
 
Top Targets:
NR LBD PPAR(28)
 
 
 
NR LBD TR(19)
 
 
NR LBD AR(15)
 
 
 
NR LBD ER(15)
 
 
 
NR LBD GR(12)
 
 
BioAssay Types:
Confirmatory(424)
 
 
 
Literature(38)
 
 
 
 
 
Summary(24)
 
 
 
BioActivity Types:
Potency(368)
 
 
 
Kd(5)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 273    Data Row: 529   Total Pages: 11   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179304]
Kd 27Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102E double mutant expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry [AID728447, Type: Literature]
View
2
[SID46392176]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Hiv Integrase Core Domain Complexed With A Derivative Of Tetraphenyl Arsonium. [gi:13786709]
View
3
[SID48413264]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
View
4
[SID48413264]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
View
5
[SID48413264]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
6
[SID48414934]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
View
7
[SID48413264]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
8
[SID46392408]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, A Cavity-Containing Mutant Of T4 Lysozyme Is Stabilized By Buried Benzene [gi:157831738]
View
9
[SID46393762]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Generating Ligand Binding Sites In T4 Lysozyme Using Deficiency-Creating Substitutions [gi:157834474]
View
10
[SID46393763]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Generating Ligand Binding Sites In T4 Lysozyme Using Deficiency-Creating Substitutions [gi:157834478]
View
11
[SID46393179]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Gcn4-Leucine Zipper Core Mutant As N16a Complexed With Benzene [gi:157880156]
View
12
[SID53813070]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Complex Structure Of Sars-Cov 3c-Like Protease With Pma [gi:163931116]
View
13
[SID103179304]
Kd 175Binding affinity to Enterobacteria phage T4 lysozyme L99A mutant expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry [AID728449, Type: Literature]
View
14
[SID103179304]
Kd 175Dissociation constant against T4 lysozyme mutant L99A [AID238119, Type: Literature]Lysozyme [gi:126605]
View
15
[SID103179304]
Kd 480Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102H double mutant expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry [AID728450, Type: Literature]
View
16
[SID103179304]
LC50 382825Toxicity determined using Golden Orfe Fish Test [AID101345, Type: Literature]
View
17
[SID103179304]
LC50 8.12831e+08The toxicity of compound was determined using Konemann's Industrial Pollutants Toxicity Test [AID162230, Type: Literature]
View
18
[SID103179304]
Toxicity determined using Tadpole Narcosis Test [AID212400, Type: Literature]
View
19
[SID103179304]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
View
20
[SID103179304]
Toxicity determined using Microtox Test [AID159270, Type: Literature]
View
21
[SID103179304]
Aqueous solubility [AID19262, Type: Literature]
View
22
[SID103179304]
logD (measured by HPLC) (as log k') [AID23960, Type: Literature]
View
23
[SID103179304]
logD (measured by HPLC) (as log k') [AID23961, Type: Literature]
View
24
[SID103179304]
logD (measured by HPLC) (as log k') [AID23963, Type: Literature]
View
25
[SID103179304]
logD (measured by HPLC) (as log k') [AID23965, Type: Literature]
View
26
[SID103179304]
logD (measured by HPLC) (as log k') [AID23968, Type: Literature]
View
27
[SID103179304]
logD (measured by HPLC) (as log k') [AID23970, Type: Literature]
View
28
[SID103179304]
logD (measured by HPLC) (as log k') [AID23971, Type: Literature]
View
29
[SID103179304]
Partition coefficient (logD, measured by HPLC, log k') [AID23973, Type: Literature]
View
30
[SID103179304]
Partition coefficient (logP) [AID24226, Type: Literature]
View
31
[SID103179304]
logBB, log(C brain / C blood) [AID26047, Type: Literature]
View
32
[SID103179304]
Partition coefficient (logD7.4) [AID26296, Type: Literature]
View
33
[SID103179304]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
View
34
[SID103179304]
In-vitro air to lung partition coefficients of the compound, logK(lung) (human/rat) [AID603950, Type: Literature]
View
35
[SID103179304]
In-vitro air to blood partition coefficients of the compound, logK(blood) (human/rat) [AID603951, Type: Literature]
View
36
[SID103179304]
In-vitro blood to lung partition coefficients of the compound, logP(lung) (human/rat) [AID603952, Type: Literature]
View
37
[SID103179304]
Octanol-water partition coefficient, log P of the compound [AID603957, Type: Literature]
View
38
[SID17389168]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
39
[SID103179304]
Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102H double mutant expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 2 mM at pH 5.4 by circular dichroism analysis [AID728442, Type: Literature]
View
40
[SID103179304]
Binding affinity to Enterobacteria phage T4 lysozyme L99A/M102H double mutant expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature at 1 mM at pH 5.4 by circular dichroism analysis [AID728444, Type: Literature]
View
41
[SID103179304]
Selectivity ratio of Kd for Enterobacteria phage T4 lysozyme L99A/M102H double mutant to Kd for Enterobacteria phage T4 lysozyme L99A/M102Q double mutant [AID728445, Type: Literature]
View
42
[SID26757303]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
43
[SID17390025]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
44
[SID26757302]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
45
[SID17389168]
Potency 7.9433qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
46
[SID144209685]
Potency-Replicate_1 67.4751qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
47
[SID144209685]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
48
[SID144209685]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
49
[SID144209685]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
50
[SID144209685]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View