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MLS001205038 (CID 23724230) - Compound BioActivity Data
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BioActivity Outcomes:
Active(84)
 
 
Inactive(467)
 
 
Inconclusive(45)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(37)
 
 
 
KCNQ channel(8)
 
 
 
STKc MAP4K3 l..(7)
 
 
 
Esterase lipa..(5)
 
 
 
TRP 2(5)
 
 
BioAssay Types:
Screening(396)
 
 
 
Confirmatory(185)
 
 
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(128)
 
 
 
 
 
IC50(31)
 
 
 
EC50(24)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 546    Data Row: 597   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID47201220]
Potency 0.092qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID47201220]
EC50_uM 0.104Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to RAS-Dependent BJ-TERT-LT-ST Fibroblast [AID2631, Type: confirmatory]
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3
[SID47201220]
EC50_MICROM 0.14Dose Response Confirmation via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 2 Wildtype [AID1897, Type: confirmatory]mitogen-activated protein kinase kinase kinase kinase 2 [Homo sapiens] [gi:22035600]
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4
[SID47201220]
EC50 0.164Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT RAS-Independent Fibroblast [AID1933, Type: confirmatory]
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5
[SID47201220]
Potency 0.2311qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID47201220]
EC50_MICROM 0.27Dose Response Confirmation Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 3 Wildtype [AID1896, Type: confirmatory]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
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7
[SID47201220]
EC50 0.395Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to DRD Non-Viral Oncogenic Fibroblast [AID1934, Type: confirmatory]
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8
[SID47201220]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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9
[SID47201220]
Potency 1VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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10
[SID47201220]
EC50 2.674Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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11
[SID47201220]
EC50 3.135Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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12
[SID47201220]
Potency 3.1623qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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13
[SID47201220]
Potency 3.5481qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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14
[SID47201220]
Potency 5.1735qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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15
[SID47201220]
Potency 9.285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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16
[SID47201220]
Potency 9.9597Activators of T cell receptors: Hit Validation [AID624298, Type: confirmatory]T cell receptor, partial [Homo sapiens] [gi:553160]
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17
[SID47201220]
Potency 12.5893qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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18
[SID47201220]
EC50 15.521Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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19
[SID47201220]
EC50_MICROM 25.88Dose Response of Screen to Find Inhibitors of Pathogenic Pemphigus Antibodies, using Cherry Pick 1 compounds [AID602251, Type: confirmatory]
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20
[SID47201220]
Potency 35.4813qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
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