Bookmark and Share
AGN-PC-047KIA (CID 23724194) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(80)
 
 
Inactive(469)
 
 
Inconclusive(35)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(25)
 
 
 
7TM GPCR Srsx(16)
 
 
 
TRP 2(9)
 
 
 
CAP ED(5)
 
 
Lactamase B(5)
 
 
 
BioAssay Types:
Screening(387)
 
 
 
 
Confirmatory(181)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(126)
 
 
 
 
 
IC50(32)
 
 
 
 
EC50(14)
 
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 535    Data Row: 585   Total Pages: 30   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID47200698]
AbsAC26_uM 0.638Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_Dose_CherryPick_Activity [AID624491, Type: confirmatory]
View
2
[SID47200698]
Potency 1.1582qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
3
[SID47200698]
Potency 1.4581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
4
[SID92117383]
IC50 1.6Late stage assay provider results from the probe development effort to identify inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (M18AAP): radiolabel-based cell-based dose response assay to identify compounds that inhibit P. falciparum growth in RBCs [AID489011, Type: confirmatory]
View
5
[SID47200698]
AC50_uM 1.87Identification of Inhibitors of RAD54 Measured in Biochemical System Using Plate Reader - 2159-01_Inhibitor_Dose_CherryPick_Activity [AID651657, Type: confirmatory]DNA repair and recombination protein RAD54-like [Homo sapiens] [gi:216548193]
View
6
[SID47200698]
IC50 2.487QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). [AID2195, Type: confirmatory]M18 aspartyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23505220]
View
7
[SID47200698]
AC50_uM 2.764HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_Dose_CherryPick_Activity [AID493248, Type: confirmatory]FAD-linked sulfhydryl oxidase ALR [Homo sapiens] [gi:54112432]
View
8
[SID47200698]
Potency 3.0131qHTS Assay for the Inhibitors of FEN1: Confirmatory Assay for Cherry-picked Compounds [AID720498, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
View
9
[SID47200698]
Potency 3.2944Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
10
[SID47200698]
Potency 5.0119qHTS of D3 Dopamine Receptor Agonist: D2 Dopamine Receptor B-arrestin Agonist Counterscreen [AID720507, Type: confirmatory]
View
11
[SID47200698]
IC50 6.72A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag - Counter Screen [AID2501, Type: confirmatory]
View
12
[SID47200698]
Potency 7.0795qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
View
13
[SID47200698]
IC50 8.41Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents [AID1903, Type: confirmatory]large T antigen [Simian virus 40] [gi:297591903]
View
14
[SID47200698]
Potency 10qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
View
15
[SID47200698]
EC50 10.13Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 [AID1960, Type: confirmatory]Zinc finger protein mex-5 [gi:55976631]
View
16
[SID47200698]
Potency 11.2202qHTS of D3 Dopamine Receptor Agonist: D3 Dopamine Receptor B-arrestin Agonist Confirmatory Assay [AID720506, Type: confirmatory]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
View
17
[SID47200698]
Potency 13.1154Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
18
[SID47200698]
Potency 17.7828qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
View
19
[SID47200698]
Potency 23.1093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View
20
[SID47200698]
AC50_uM 25.5Identification of Rad54 Inhibitors - Ruling Out Compounds That Bind DNA Measured in Biochemical System Using Plate Reader - 2159-04_Inhibitor_Dose_CherryPick_Activity [AID651673, Type: confirmatory]
View