Cyclic AMP sodium (CID 23669773) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(13)
 
 
Inactive(385)
 
 
Inconclusive(7)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(15)
 
 
STKc PKA(10)
 
 
 
7TM GPCR Srsx(6)
 
 
TRP 2(5)
 
 
alkPPc(4)
 
 
BioAssay Types:
Screening(295)
 
 
 
 
Confirmatory(94)
 
 
 
 
 
Literature(13)
 
 
 
BioActivity Types:
Potency(82)
 
 
 
 
 
IC50(11)
 
 
EC50(6)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 406    Data Row: 406   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56320726]
EC50 0.06798Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R1A (PKA-R1A) complex [AID504887, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 1 [Mus musculus] [gi:6755076]
View
2
[SID56320726]
EC50 0.06798Counterscreen for activators of the Protein Kinase A-R2B (PKA-R2B) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify activators of the Protein Kinase A-R1A (PKA-R1A) complex [AID504896, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 1 [Mus musculus] [gi:6755076]
View
3
[SID56320726]
EC50 0.08846Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504888, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
4
[SID56320726]
EC50 0.08846Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504888, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
5
[SID56320726]
EC50 0.08846Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504888, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
6
[SID56320726]
EC50 0.08846Counterscreen for activators of the Protein Kinase A-R1A (PKA-R1A) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504893, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
7
[SID56320726]
EC50 0.08846Counterscreen for activators of the Protein Kinase A-R1A (PKA-R1A) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504893, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
8
[SID56320726]
EC50 0.08846Counterscreen for activators of the Protein Kinase A-R1A (PKA-R1A) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504893, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
9
[SID56320726]
Potency 0.0974qHTS Assay for Agonists of the Relaxin Receptor RXFP1: RXFP1 Hit Validation [AID489012, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
View
10
[SID56320726]
Potency 0.0974qHTS Assay for Agonists of the Relaxin Receptor RXFP1: RXFP1 Hit Validation [AID489012, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
View
11
[SID56320726]
Potency 0.1944qHTS Assay for Agonists of the Relaxin Receptor RXFP1: V1B Hit Validation [AID492948, Type: confirmatory]vasopressin V1b receptor [Homo sapiens] [gi:4502333]
View
12
[SID56320726]
Potency 0.1944qHTS Assay for Agonists of the Relaxin Receptor RXFP1: V1B Hit Validation [AID492948, Type: confirmatory]vasopressin V1b receptor [Homo sapiens] [gi:4502333]
View
13
[SID56320726]
Potency 0.1944qHTS Assay for Agonists of the Relaxin Receptor RXFP1: V1B Hit Validation [AID492948, Type: confirmatory]vasopressin V1b receptor [Homo sapiens] [gi:4502333]
View
14
[SID56320726]
Potency 0.2181qHTS Assay for Agonists of the Relaxin Receptor RXFP1: THP1 Hit Validation [AID492949, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
View
15
[SID56320726]
Potency 0.2181qHTS Assay for Agonists of the Relaxin Receptor RXFP1: THP1 Hit Validation [AID492949, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
View
16
[SID56320726]
Potency 0.2181qHTS Assay for Agonists of the Relaxin Receptor RXFP1: RXFP2 Hit Validation [AID489043, Type: confirmatory]relaxin receptor 2 isoform 1 [Homo sapiens] [gi:18677729]
View
17
[SID56320726]
Potency 0.2181qHTS Assay for Agonists of the Relaxin Receptor RXFP1: RXFP2 Hit Validation [AID489043, Type: confirmatory]relaxin receptor 2 isoform 1 [Homo sapiens] [gi:18677729]
View
18
[SID56320726]
Potency 1.2589qHTS Assay for Agonists of the Relaxin Receptor RXFP1 [AID2676, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
View
19
[SID56320726]
Potency 1.2589qHTS Assay for Agonists of the Relaxin Receptor RXFP1 [AID2676, Type: confirmatory]relaxin receptor 1 isoform 1 [Homo sapiens] [gi:85986601]
View
20
[SID56320726]
 Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R1A (PKA-R1A) complex [AID504707, Type: screening]cAMP-dependent protein kinase catalytic subunit beta isoform 1 [Mus musculus] [gi:6755076]
View
21
[SID56320726]
 Fluorescence polarization-based biochemical high throughput confirmation assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504797, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
22
[SID56320726]
 Fluorescence polarization-based biochemical high throughput confirmation assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504797, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
23
[SID56320726]
 Fluorescence polarization-based biochemical high throughput confirmation assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504797, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
24
[SID56320726]
 Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504700, Type: screening]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
25
[SID56320726]
 Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504700, Type: screening]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
26
[SID56320726]
 Fluorescence polarization-based biochemical primary high throughput screening assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex [AID504700, Type: screening]cAMP-dependent protein kinase catalytic subunit beta isoform 3 [Homo sapiens] [gi:46909587]
View
27
[SID56320726]
 Fluorescence polarization-based biochemical high throughput confirmation assay for activators of the Protein Kinase A-R1A (PKA-R1A) complex [AID504800, Type: Literature]cAMP-dependent protein kinase catalytic subunit beta isoform 1 [Mus musculus] [gi:6755076]
View
28
[SID56320726]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
29
[SID56320726]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
30
[SID56320726]
Potency 0.7943qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624288, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
View
31
[SID56320726]
Potency 14.7157Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
32
[SID56320726]
EC50 113.738Counterscreen for activators of the Protein Kinase A-R1A (PKA-R1A) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify fluorescence polarization assay artifacts [AID504883, Type: Literature]
View
33
[SID56320726]
EC50 113.738Counterscreen for activators of the Protein Kinase A-R2B (PKA-R2B) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify fluorescence polarization assay artifacts [AID504890, Type: Literature]
View
34
[SID56320726]
 Small Molecules that selectively kill Giardia lamblia: qHTS [AID540267, Type: screening]
View
35
[SID56320726]
 Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening]
View
36
[SID56320726]
 MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint_HTS_Activity [AID588334, Type: screening]
View
37
[SID56320726]
 Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Absorbance-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) full deck assay to identify assay artifacts [AID588335, Type: screening]
View
38
[SID56320726]
 HTS to Find Inhibitors of Pathogenic Pemphigus Antibodies [AID588358, Type: screening]
View
39
[SID56320726]
 Cholera Quorum: HTS for inducers of light production in the absence ofautoinducers using BH1578 (luxS deficient, cqsA deficient) Measured in Microorganism System Using Plate Reader - 2132-01_Agonist_SinglePoint_HTS_Activity [AID588436, Type: screening]
View
40
[SID56320726]
 uHTS identification of small molecule modulators of myocardial damage [AID588492, Type: screening]
View
41
[SID56320726]
 Schnurri-3 Inhibitors: specific inducers of adult bone formation Measured in Cell-Based System Using Plate Reader - 2134-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588674, Type: screening]
View
42
[SID56320726]
 Luciferase Reporter Cell Based HTS to identify inhibitors of N-linked Glycosylation Measured in Cell-Based System Using Plate Reader - 2146-01_Inhibitor_SinglePoint_HTS_Activity_Set2 [AID588692, Type: screening]
View
43
[SID56320726]
IC50 A Cell-Based Confirmatory Screen for Compounds that Inhibit VEEV, TC-83 [AID588727, Type: confirmatory]
View
44
[SID56320726]
Potency qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
View
45
[SID56320726]
 uHTS determination of small molecule cytotoxicity in a fluorescence assay to identify cystic fibrosis induced NFkb Inhibitors [AID602141, Type: screening]
View
46
[SID56320726]
 Full deck counterscreen for positive allosteric modulators (PAMs) of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602247, Type: screening]
View
47
[SID56320726]
 Full deck counterscreen for agonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective activators and assay artifacts using the parental CHOK1 cell line [AID602248, Type: screening]
View
48
[SID56320726]
 Full deck counterscreen for antagonists of the human M1 muscarinic receptor (CHRM1): Fluorescence-based cell-based high throughput screening assay to identify nonselective inhibitors and assay artifacts using the parental CHOK1 cell line [AID602250, Type: screening]
View
49
[SID56320726]
 uHTS luminescent assay for identification of compounds that enhance the survival of human induced pluripotent stem cells when cultured as single cells [AID602274, Type: screening]
View
50
[SID56320726]
 HTS for suppressors of simvastatin-induced mytoxicity in differentiated C2C12 cells Measured in Cell-Based System Using Plate Reader - 2112-01_Suppressor_SinglePoint_HTS_Activity [AID602340, Type: screening]
View