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tanshinone II A sodium sulfonate (CID 23669322) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(60)
 
 
Inconclusive(9)
 
 
Unspecified(4)
 
 
Top Targets:
Esterase lipa..(6)
 
 
 
PLDc mTdp1 2(3)
 
 
HSD10-like SD..(2)
 
 
globin(2)
 
 
STKc ERK1 2 l..(2)
 
 
BioAssay Types:
Confirmatory(68)
 
 
 
 
Literature(8)
 
 
 
 
Screening(4)
 
 
 
BioActivity Types:
Potency(66)
 
 
 
 
Ki(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 79    Data Row: 84   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID164127590]
Ki 3.9Inhibition of human iCE using o-NPA as substrate by spectrophotometric assay [AID731514, Type: Literature]Cocaine esterase [gi:46576349]
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2
[SID26749230]
Potency 8.9125Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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3
[SID26749230]
Potency 10qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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4
[SID26749230]
Potency 10qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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5
[SID26749230]
Potency 10qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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6
[SID164127590]
Ki 28.79Inhibition of human iCE using CPT-11 as substrate by spectrophotometric assay [AID731513, Type: Literature]Cocaine esterase [gi:46576349]
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7
[SID26749230]
Potency 31.6228qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM) [AID2528, Type: confirmatory]Bloom syndrome protein isoform 1 [Homo sapiens] [gi:4557365]
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8
[SID26749230]
Potency 31.6228qHTS Assay for Inhibitors of BRCT-Phosphoprotein Interaction (Green Fluorophore) [AID875, Type: confirmatory]Chain A, Solution Structure Of The Brct-C Domain From Human Brca1 [gi:159162802]
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9
[SID26749230]
Potency 35.4813qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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10
[SID92124935]
A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities [AID588519, Type: Literature]Chain A, Poliovirus Polymerase With Gtp [gi:52695378]
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11
[SID26749230]
qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia: Coupling assay counterscreen [AID2472, Type: screening]glyceraldehyde-3-phosphate dehydrogenase isoform 1 [Homo sapiens] [gi:7669492]
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12
[SID164127590]
Ki 100Inhibition of human BChE using butyrylthiocholine as substrate by spectrophotometric assay [AID731511, Type: Literature]Acetylcholinesterase [gi:113037]
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13
[SID164127590]
Ki 100Inhibition of human AChE using acetylthiocholine as substrate by spectrophotometric assay [AID731512, Type: Literature]Acetylcholinesterase [gi:113037]
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14
[SID164127590]
Ki 100Inhibition of human CE1 using o-NPA as substrate by spectrophotometric assay [AID731515, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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15
[SID164127590]
Inhibition of human iCE in human U373MG cells assessed as 4-MUA substrate hydrolysis at 1 uM after 1 hr by fluorescence spectrometry assay [AID731510, Type: Literature]Cocaine esterase [gi:46576349]
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16
[SID26749230]
Potency 10qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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17
[SID26749230]
Potency 11.2202qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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18
[SID26749230]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1: Spectroscopic Profiling in AFC Spectral Region [AID923, Type: confirmatory]
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19
[SID26749230]
Potency Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization [AID1463, Type: confirmatory]
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20
[SID26749230]
Potency qHTS Assay for Lipid Storage Modulators [AID1519, Type: confirmatory]
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