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BioActivity Data for Compound dexon (fungicide) (CID 23668198)

BioActivity Outcomes:
Active(33)
 
 
Inactive(219)
 
 
Inconclusive(58)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(18)
 
 
 
NR LBD TR(11)
 
 
 
NR LBD ER(11)
 
 
 
NR LBD AR(11)
 
 
 
 
NR LBD VDR(8)
 
 
 
BioAssay Types:
Confirmatory(260)
 
 
 
 
 
Summary(26)
 
 
 
 
Literature(2)
 
 
Screening(2)
 
 
BioAssay Categories:
Toxicity(45)
 
 
 
 
 
BioActivity Types:
Potency(238)
 
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 261    Data Row: 313   Total Pages: 16   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213963]
Potency-Replicate_1 2.169qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144213963]
Potency-Replicate_1 4.3277qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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3
[SID17389878]
Potency 5.9557qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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4
[SID17389878]
Potency 8.4127qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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5
[SID144213963]
Potency-Replicate_1 8.6349qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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6
[SID144213963]
Potency-Replicate_1 9.1004qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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7
[SID17389878]
Potency 10qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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8
[SID17389878]
Potency 10qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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9
[SID144213963]
AhR Potency (uM) 11.5812qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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10
[SID144213963]
Ratio Potency (uM) 12.6011qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID144213963]
Potency-Replicate_1 12.8547qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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12
[SID144213963]
Potency-Replicate_1 14.4232qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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13
[SID17389878]
Potency 14.9601qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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14
[SID144213963]
Potency-Replicate_1 16.2004qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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15
[SID144213963]
Potency-Replicate_1 19.3312qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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16
[SID144213963]
Potency 21.6899qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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17
[SID144213963]
Potency-Replicate_1 22.8837qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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18
[SID26752899]
Potency 24.3365qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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19
[SID144213963]
Potency 24.3365qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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20
[SID144213963]
Ratio Potency (uM) 25.0602qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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