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dexon (fungicide) (CID 23668198) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(31)
 
 
Inactive(203)
 
 
Inconclusive(61)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(18)
 
 
 
NR LBD AR(11)
 
 
 
 
NR LBD TR(11)
 
 
 
NR LBD ER(11)
 
 
 
NR LBD GR(8)
 
 
 
BioAssay Types:
Confirmatory(247)
 
 
 
 
Summary(24)
 
 
 
 
Screening(2)
 
 
Literature(1)
 
 
BioActivity Types:
Potency(228)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 246    Data Row: 297   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213963]
Potency-Replicate_1 0.0579qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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2
[SID144213963]
Potency-Replicate_1 2.169qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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3
[SID17389878]
Potency 5.9557qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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4
[SID144213963]
Potency-Replicate_1 7.2287qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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5
[SID17389878]
Potency 8.4127qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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6
[SID144213963]
Potency-Replicate_1 9.1004qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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7
[SID17389878]
Potency 10qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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8
[SID17389878]
Potency 10qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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9
[SID144213963]
AhR Potency (uM) 11.5812qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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10
[SID144213963]
Ratio Potency (uM) 12.6011qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID144213963]
Potency-Replicate_1 12.8547qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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12
[SID144213963]
Potency-Replicate_1 14.4232qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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13
[SID17389878]
Potency 14.9601qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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14
[SID144213963]
Potency-Replicate_1 19.3312qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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15
[SID144213963]
Potency 21.6899qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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16
[SID144213963]
Potency-Replicate_1 22.8837qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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17
[SID26752899]
Potency 24.3365qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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18
[SID144213963]
Potency 24.3365qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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19
[SID144213963]
Ratio Potency (uM) 25.0602qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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20
[SID17389878]
Potency 37.578qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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21
[SID26752899]
Potency-Replicate_1 54.4827qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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22
[SID26752899]
Potency 70.7946qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway [AID651777, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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23
[SID17389878]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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24
[SID17389878]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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25
[SID26752899]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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26
[SID26752899]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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27
[SID26752899]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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28
[SID17389878]
Cell Viability - N2a [AID540, Type: confirmatory]
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29
[SID17389878]
Cell Viability - H-4-II-E [AID543, Type: confirmatory]
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30
[SID48413774]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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31
[SID17389878]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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32
[SID17389878]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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33
[SID26752899]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
34
[SID26752899]
Potency 0.5623qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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35
[SID144213963]
Potency-Replicate_1 2.7306qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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36
[SID144213963]
Potency-Replicate_1 5.7893qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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37
[SID144213963]
Potency-Replicate_1 6.1131qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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38
[SID17389878]
Potency 19.9526qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
View
39
[SID144213963]
Potency-Replicate_1 21.8724qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
40
[SID144213963]
Potency-Replicate_1 25.6485qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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41
[SID144213963]
Potency-Replicate_1 51.1754qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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42
[SID144213963]
Potency-Replicate_1 72.2872qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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43
[SID144213963]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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44
[SID144213963]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
45
[SID144213963]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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46
[SID17389878]
Potency qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
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47
[SID17389878]
Potency qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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48
[SID26752899]
Potency qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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49
[SID17389878]
Potency qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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50
[SID17389878]
Potency qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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