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cerivastatin (CID 23663992) - Compound BioActivity Data
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BioActivity Outcomes:
Active(20)
 
 
Inactive(169)
 
 
Inconclusive(32)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD ER(7)
 
 
 
NR LBD AR(7)
 
 
 
 
TRP 2(5)
 
 
NR LBD VDR(4)
 
 
 
BioAssay Types:
Screening(106)
 
 
 
Confirmatory(85)
 
 
 
 
Summary(24)
 
 
 
 
Literature(3)
 
 
BioActivity Types:
Potency(85)
 
 
 
 
IC50(9)
 
 
EC50(7)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 219    Data Row: 224   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205797]
Potency-Replicate_1 0.0133qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144205797]
Potency-Replicate_1 0.075qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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3
[SID49681715]
EC50_uM 0.104Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to RAS-Dependent BJ-TERT-LT-ST Fibroblast [AID2631, Type: confirmatory]
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4
[SID144205797]
Ratio Potency (uM) 0.197391qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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5
[SID144205797]
Potency-Replicate_1 0.2985qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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6
[SID144205797]
Potency 0.5957qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID144205797]
Potency 1.1886qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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8
[SID144205797]
Potency-Replicate_1 3.378qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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9
[SID144205797]
TR Potency (uM) 10.5909qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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10
[SID144205797]
Potency-Replicate_1 11.8832qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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11
[SID144205797]
Potency-Replicate_1 11.8832qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID144205797]
Potency-Replicate_1 13.3332qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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13
[SID49681715]
Fluorescence Cell-Based Primary HTS of C.albicans growth in the presence of Fluconazole and compound [AID1979, Type: screening]heat shock protein 90 [Candida albicans] [gi:994798]
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14
[SID49681715]
SAMPLE2_EC50_uM Fluorescence Cell-Based Dose Response to Characterize Compounds Cytotoxic to RAS-Dependent BJeLR Fibroblast [AID2610, Type: confirmatory]
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15
[SID103770546]
HMG-CoA reductase inhibitor [AID742465, Type: other]3-hydroxy-3-methylglutaryl-coenzyme A reductase [gi:123343]
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16
[SID49681715]
MLPCN Ras selective lethality-BJeLR viability [AID1554, Type: screening]
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17
[SID49681715]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - inhibitors [AID1813, Type: screening]
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18
[SID49681715]
Luminescence Cell-Based/Microorganism Primary HTS to Identify Inhibitors of T.Cruzi Replication [AID1885, Type: screening]
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19
[SID49681715]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Cancer Stem Cells [AID2717, Type: screening]
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20
[SID144205797]
qHTS assay to identify aromatase inhibitors: Summary [AID743139, Type: summary]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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