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BioActivity Data for Compound sivelestat sodium hydrate (CID 23663985)

BioActivity Outcomes:
Active(7)
 
 
Inactive(109)
 
 
Inconclusive(5)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
 
BioAssay Types:
Confirmatory(83)
 
 
 
 
 
Summary(29)
 
 
 
Screening(10)
 
 
 
BioAssay Categories:
Toxicity(6)
 
 
 
Cell-based(8)
 
 
 
BioActivity Types:
Potency(100)
 
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 122    Data Row: 122   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144206123]
Potency-Replicate_1 1.3333qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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2
[SID144206123]
Ratio Potency (uM) 5.35378qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway: Summary [AID743053, Type: summary]AR protein [Homo sapiens] [gi:124375976]
View
3
[SID144206123]
Potency-Replicate_1 6.007qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway [AID743036, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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4
[SID144206123]
AhR Potency (uM) 11.8832qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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5
[SID144206123]
Potency-Replicate_1 11.8832qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID170465996]
SW480 viability from Cell TiterGlo-screen [AID1117343, Type: screening]
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7
[SID170465996]
GSK3B-pretreated HCT116 viability from Cell TiterGlo-screen [AID1117336, Type: screening]
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8
[SID170465996]
AC50 (uM) qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green channel [AID1117298, Type: confirmatory]
View
9
[SID170465996]
Ac50 2.51189qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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10
[SID170465996]
AC50 (uM) 2.5119qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel [AID1117305, Type: confirmatory]
View
11
[SID170465996]
AC50 (uM) 3.5481qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
View
12
[SID170465996]
Ac50 3.54813qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
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13
[SID170465996]
nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-screen [AID1117326, Type: screening]
View
14
[SID170465996]
DLD-1 viability from Cell TiterGlo-screen [AID1117346, Type: screening]
View
15
[SID170465996]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID1159520, Type: confirmatory]
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16
[SID170465996]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway - cell viability counter screen [AID1159517, Type: confirmatory]
View
17
[SID170465996]
HCT116 viability from Cell TiterGlo-screen [AID1117342, Type: screening]
View
18
[SID170465996]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway [AID1159526, Type: confirmatory]
View
19
[SID170465996]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the NFkB signaling pathway - cell viability counter screen [AID1159515, Type: confirmatory]
View
20
[SID170465996]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway - cell viability counter screen [AID1159525, Type: confirmatory]
View