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tazobactam (CID 23663400) - Compound BioActivity Data
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BioActivity Outcomes:
Active(32)
 
 
Inactive(66)
 
 
Inconclusive(20)
 
 
Unspecified(61)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
 
NR LBD ER(7)
 
 
 
 
NR LBD AR(7)
 
 
 
Beta-lactamas..(6)
 
 
 
PRK15442(4)
 
 
 
BioAssay Types:
Literature(85)
 
 
 
 
Confirmatory(68)
 
 
 
 
Summary(24)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(86)
 
 
 
 
IC50(27)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 179    Data Row: 179   Total Pages: 9   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103512768]
IC50 0.025The concentration of compound to inhibit Beta-lactamase was measured on Escherichia coli WC3310 [AID43575, Type: Literature]Beta-lactamase TEM [gi:50401825]
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2
[SID103512768]
IC50 0.06Inhibitory activity against TEM-1 (class A) beta-lactamase [AID44070, Type: Literature]
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3
[SID103512768]
IC50 0.06Inhibitory activity against TEM-1 (class A) beta-lactamase [AID44071, Type: Literature]
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4
[SID103512768]
IC50 0.1Inhibition of Escherichia coli TEM1 [AID282059, Type: Literature]Beta-lactamase TEM [gi:50401825]
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5
[SID103512768]
IC50 0.1Inhibition of TEM1 beta-lactamase [AID315682, Type: Literature]
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6
[SID103512768]
IC50 0.122Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzyme [AID200367, Type: Literature]
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7
[SID103512768]
IC50 0.29The compound was evaluated for inhibition against Beta-lactamase TEM derived from Staphylococcus aureus [AID44225, Type: Literature]Beta-lactamase [gi:115038]
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8
[SID103512768]
IC50 0.297Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureus [AID44224, Type: Literature]Beta-lactamase [gi:115038]
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9
[SID103512768]
IC50 0.32Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacae [AID50693, Type: Literature]TEM-1 beta-lactamase [gi:75440591]
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10
[SID103512768]
IC50 0.943The concentration of compound to inhibit Beta-lactamase was measured on Enterobacter cloacae P99 [AID43282, Type: Literature]Beta-lactamase [gi:113727]
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11
[SID144205137]
Potency-Replicate_1 1.0682qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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12
[SID144205137]
Ratio Potency (uM) 1.39742qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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13
[SID144205137]
Potency-Replicate_1 2.3914qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID103512768]
IC50 2.57Inhibitory activity against serine beta-lactamase, PC1 (class A) derived from Staphylococcus aureus [AID43916, Type: Literature]Beta-lactamase [gi:115038]
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15
[SID103512768]
IC50 2.57The compound was evaluated for inhibition against Beta-lactamase derived from Staphylococcus aureus [AID43919, Type: Literature]Beta-lactamase [gi:115038]
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16
[SID103512768]
IC50 2.8Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1 [AID50699, Type: Literature]Beta-lactamase [gi:115038]
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17
[SID103512768]
IC50 3.4The compound was evaluated for inhibition against the GC1 extended spectrum Class C beta-lactamase [AID50710, Type: Literature]
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18
[SID144205137]
Ratio Potency (uM) 3.93847qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID103512768]
IC50 4The concentration of compound to inhibit Beta-lactamase was measured on Enterobacter cloacae SC 12368 [AID43405, Type: Literature]Beta-lactamase [gi:113727]
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20
[SID103512768]
IC50 47.7Inhibitory activity against AmpC (class C) beta-lactamase [AID44068, Type: Literature]
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