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BioActivity Data for Compound MLS001066435 (CID 23641006)

BioActivity Outcomes:
Active(8)
 
 
Inactive(466)
 
 
Inconclusive(10)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(35)
 
 
Esterase lipa..(5)
 
 
CAP ED(5)
 
 
TRP 2(5)
 
 
RasGEF(4)
 
 
BioAssay Types:
Screening(352)
 
 
 
 
Confirmatory(118)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(106)
 
 
Toxicity(6)
 
 
Cell-based(121)
 
 
 
 
Organism-base..(13)
 
 
 
BioActivity Types:
Potency(100)
 
 
 
 
IC50(11)
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 443    Data Row: 485   Total Pages: 25   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46501096]
AC50_uM 0.326HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_Dose_CherryPick_Activity [AID652057, Type: confirmatory]
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2
[SID46501096]
AC50_uM 0.509Control Cell Fusion Counterscreen Assay Measured in Cell-Based System Using Plate Reader - 7013-02_Inhibitor_Dose_CherryPick_Activity [AID652040, Type: confirmatory]
View
3
[SID46501096]
AC50_uM 0.581Cell fusion assay for clade C HIV-1ZM109 Env Measured in Cell-Based System Using Plate Reader - 7013-05_Inhibitor_Dose_CherryPick_Activity [AID652058, Type: confirmatory]
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4
[SID46501096]
AC50_uM 0.627HIV-1 Cell Fusion assay for clade B Env AD8 Measured in Cell-Based System Using Plate Reader - 7013-04_Inhibitor_Dose_CherryPick_Activity [AID652062, Type: confirmatory]
View
5
[SID46501096]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
View
6
[SID46501096]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the GAA850 frataxin (FXN) promoter [AID540364, Type: screening] [geneid:2395]
View
7
[SID46501096]
Counterscreen for activators of the GAA850 frataxin promoter: luminescence-based cell-based high throughput screening assay to identify activators of the GAA30 frataxin promoter [AID588350, Type: screening] [geneid:2395]
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8
[SID46501096]
Luminescence-based cell-based high throughput confirmation assay for activators of the GAA850 frataxin (FXN) promoter [AID588351, Type: screening] [geneid:2395]
View
9
[SID46501096]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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10
[SID46501096]
Potency 1.9953qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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11
[SID46501096]
Potency 19.9526qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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12
[SID46501096]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
View
13
[SID46501096]
Fluorescence-based biochemical primary high throughput screening assay to identify activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493008, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
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14
[SID46501096]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) [AID493244, Type: screening]cardiac alpha tropomyosin [Sus scrofa] [gi:1927]
View
15
[SID46501096]
uHTS identification of agonists of the CRF-binding protein and CRF-R2 receptor complex [AID588473, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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16
[SID46501096]
uHTS identification of antagonists of the CRF-binding protein and CRF-R2 receptor complex [AID588475, Type: screening]corticotropin releasing factor-binding protein [Homo sapiens] [gi:30219]
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17
[SID46501096]
Potency qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy [AID624291, Type: confirmatory]Glycoprotein hormones alpha chain [gi:121312]
View
18
[SID46501096]
Potency qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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19
[SID46501096]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ CIT2_MLPCN. [AID2029, Type: screening]citrate synthase 2, partial [Saccharomyces cerevisiae] [gi:171229]
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20
[SID46501096]
Potency Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS [AID504937, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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