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T6266407 (CID 2362078) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(4)
 
 
Top Targets:
Peptidase M17(2)
 
 
 
M1 APN 1(1)
 
 
PTZ00371(1)
 
 
BioAssay Types:
Confirmatory(8)
 
 
 
BioActivity Types:
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID104233676]
Average PFM17LAP IC50 10.85QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588688, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23497510]
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2
[SID104233676]
CC50 41.08A Cell Based Secondary Assay to Explore Cytotoxicity in THP-1 Cells of Compounds that Modulate Mycobacterium tuberculosis in Media Containing Glycerol versus Media without Glycerol (2) [AID504683, Type: confirmatory]
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3
[SID104233676]
Average CC50 50Vero Cytoxicity Assay: A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Plasmodium falciparum M1 Aspartyl Aminopeptidase (PFM17LAP) [AID588707, Type: confirmatory]
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4
[SID104233676]
CC50 56.022A Cell Based Secondary Assay To Explore Vero Cell Cytotoxicity of Purified and Synthesized Compounds that Inhibit Mycobacterium Tuberculosis (3) [AID504684, Type: confirmatory]
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5
[SID104233676]
Average HUM17LAP IC50 Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Human M17LAP (HUM17LAP) [AID602214, Type: confirmatory]leucine aminopeptidase [Homo sapiens] [gi:4335941]
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6
[SID104233676]
Average PFM18AAP IC50 Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) [AID588697, Type: confirmatory]M18 aspartyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23505220]
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7
[SID104233676]
Average PFM1AAP IC50 Counterscreen for inhibitors of PFM17LAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) [AID588698, Type: confirmatory]m1-family aminopeptidase [Plasmodium falciparum 3D7] [gi:23615263]
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8
[SID104233676]
CC50 A Cell Based Secondary Assay to Explore Cytotoxicity in HepG2 Cells of Compounds that Modulate Mycobacterium tuberculosis in Media Containing Glycerol versus Media without Glycerol (2) [AID504682, Type: confirmatory]
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