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didecyldimethylammonium (CID 23558) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(27)
 
 
Inactive(24)
 
 
Inconclusive(40)
 
 
Unspecified(6)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
 
 
NR LBD ER(7)
 
 
 
NR LBD Fxr(4)
 
 
NR LBD VDR(4)
 
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
 
Summary(24)
 
 
 
Literature(11)
 
 
 
 
BioActivity Types:
Potency(80)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 97    Data Row: 97   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210915]
Potency-Replicate_1 0.3438qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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2
[SID144210915]
Potency-Replicate_1 0.4328qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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3
[SID144210915]
Potency-Replicate_1 0.4328qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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4
[SID144210915]
Potency-Replicate_1 9.6885qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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5
[SID144210915]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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6
[SID144210915]
Potency-Replicate_1 15.4845qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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7
[SID144210915]
Potency-Replicate_1 15.4845qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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8
[SID144210915]
Potency-Replicate_1 19.3312qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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9
[SID144210915]
Potency-Replicate_1 19.4938qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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10
[SID144210915]
Potency-Replicate_1 19.4938qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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11
[SID144210915]
Potency-Replicate_1 19.4938qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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12
[SID144210915]
Potency-Replicate_1 21.8724qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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13
[SID144210915]
Potency-Replicate_1 24.3365qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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14
[SID144210915]
Potency-Replicate_1 24.3365qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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15
[SID144210915]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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16
[SID144210915]
Potency-Replicate_1 30.6379qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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17
[SID144210915]
Potency-Replicate_1 34.6654qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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18
[SID144210915]
Potency-Replicate_1 38.8952qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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19
[SID144210915]
Potency-Replicate_1 43.2771qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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20
[SID144210915]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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21
[SID144210915]
Potency-Replicate_1 54.941qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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22
[SID144210915]
Potency-Replicate_1 61.1306qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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23
[SID144210915]
Potency-Replicate_1 61.1306qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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24
[SID103510667]
Internal Potassium leakage in Staphylococcus aureus ATCC 6538 at 9 ug/ml [AID278515, Type: Literature]
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25
[SID103510667]
Loss of membrane integrity in Staphylococcus aureus ATCC 6538 at above 4.5 ug/ml [AID278516, Type: Literature]
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26
[SID103510667]
Induction of membrane collapse in Staphylococcus aureus ATCC 6538 at 12 ug/ml [AID278517, Type: Literature]
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27
[SID103510667]
Induction of autolysis in Staphylococcus aureus ATCC 6538 at 9 ug/ml [AID278519, Type: Literature]
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28
[SID103510667]
Reduction of cell count in Staphylococcus aureus ATCC 6538 between 6 to 18 hrs exposure [AID278518, Type: Literature]
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29
[SID103510667]
Antibacterial activity against 10^5 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs [AID278510, Type: Literature]
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30
[SID103510667]
Antibacterial activity against 10^6 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs [AID278511, Type: Literature]
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31
[SID103510667]
Antibacterial activity against 10^7 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs [AID278512, Type: Literature]
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32
[SID103510667]
Antibacterial activity against 10^8 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs [AID278513, Type: Literature]
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33
[SID103510667]
Antibacterial activity against 10^9 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs [AID278514, Type: Literature]
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34
[SID144210915]
Potency-Replicate_1 61.6448qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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35
[SID144210915]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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36
[SID144210915]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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37
[SID144210915]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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38
[SID144210915]
AhR Potency (uM) qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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39
[SID144210915]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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40
[SID144210915]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743241, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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41
[SID144210915]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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42
[SID144210915]
ATAD5 Potency (uM) qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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43
[SID103510667]
Intracellular coagulation in Staphylococcus aureus ATCC 6538 at tested concentrations 4.5, 9, 12 and 15 ug/ml [AID278520, Type: Literature]
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44
[SID144210915]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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45
[SID144210915]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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46
[SID144210915]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cell free culture [AID720684, Type: confirmatory]
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47
[SID144210915]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
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48
[SID144210915]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cell free culture [AID720686, Type: confirmatory]
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49
[SID144210915]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
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50
[SID144210915]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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