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benzyl benzoate (CID 2345) - Compound BioActivity Data
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BioActivity Outcomes:
Active(7)
 
 
Inactive(893)
 
 
Inconclusive(52)
 
 
Unspecified(57)
 
 
Top Targets:
NR LBD PPAR(29)
 
 
 
7tm 4(29)
 
 
NR LBD AR(23)
 
 
NR LBD ER(23)
 
 
NR LBD VDR(17)
 
 
 
BioAssay Types:
Confirmatory(409)
 
 
 
 
Screening(341)
 
 
 
Literature(122)
 
 
 
 
 
Summary(72)
 
 
 
BioActivity Types:
Potency(442)
 
 
 
 
IC50(20)
 
 
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 682    Data Row: 1009   Total Pages: 51   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103378318]
IC50 1.1Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay [AID390722, Type: Literature]Hormone-sensitive lipase [gi:85690847]
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2
[SID46391754]
IC50 3.9Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Porcine Odorant Binding Protein Complexed With Benzoic Acid Phenylmethylester [gi:12084613]
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3
[SID46391754]
IC50 3.9Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Porcine Odorant Binding Protein Complexed With Benzoic Acid Phenylmethylester [gi:12084613]
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4
[SID103378318]
Acaricidal activity against Dermatophagoides pteronyssinus assessed as mortality at 9.6 to 12.7 ug/cm2 after 24 to 72 hr by fabric disk assay relative to untreated control [AID1102055, Type: Literature]
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5
[SID103378318]
Antihypertensive activity in Std:ddY mouse assessed as inhibition of increase of angiotensin 2-induced systolic arterial pressure at 2 and 10 mg/kg, po after 30 mins [AID362097, Type: Literature]
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6
[SID26753738]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_58, Type: Literature]
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7
[SID46391754]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Porcine Odorant Binding Protein Complexed With Benzoic Acid Phenylmethylester [gi:12084613]
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8
[SID103378318]
IC50 90Compound was tested for the inhibition of beta-lactamase [AID43431, Type: Literature]
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9
[SID103378318]
IC50 125Inhibition of malate dehydrogenase (MDH) [AID106801, Type: Literature]
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10
[SID103378318]
IC50 250Compound was tested for the inhibition of Chymotrypsinogen [AID52776, Type: Literature]
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11
[SID103378318]
Fold decrease in IC50 vs chymotrypsinogen on pre-incubation [AID52778, Type: Literature]
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12
[SID103378318]
Fold decrease in IC50 vs malate dehydrogenase (MDH) on pre-incubation [AID106656, Type: Literature]
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13
[SID103378318]
Fold increase in IC50 vs malate dehydrogenase (MDH) with 1 mg/ml saponin [AID106799, Type: Literature]
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14
[SID103378318]
Fold decrease in IC50 vs beta-lactamase on pre-incubation [AID43563, Type: Literature]
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15
[SID103378318]
Fold increase in IC50 vs chymotrypsinogen with 0.2 mg/ml saponin [AID52773, Type: Literature]
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16
[SID8149871]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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17
[SID8149871]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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18
[SID8149871]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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19
[SID8149871]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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20
[SID8149871]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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