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11H-Indeno[1,2-b]quinoxalin-11-one (CID 23386) - Compound BioActivity Data
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BioActivity Outcomes:
Active(39)
 
 
Inactive(726)
 
 
Inconclusive(29)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(25)
 
 
 
7TM GPCR Srsx(16)
 
 
 
alkPPc(12)
 
 
Peptidase C48(11)
 
 
 
Bcl-2 like(11)
 
 
BioAssay Types:
Screening(525)
 
 
 
 
 
Confirmatory(220)
 
 
 
 
 
Literature(13)
 
 
BioActivity Types:
Potency(146)
 
 
 
 
 
IC50(47)
 
 
 
 
EC50(18)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 728    Data Row: 797   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14723599]
EC50 0.307Luminescence Cell-Based Dose Confimation HTS to Identify Activators of 5'UTR Stem-Loop Driven Alpha-Synuclein mRNA Translation in H4 Neuroglioblastoma Cells [AID2003, Type: confirmatory]
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2
[SID14723599]
EC50 1.218Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID463088, Type: confirmatory]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
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3
[SID14723599]
Potency 2.2387qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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4
[SID14723599]
Potency 2.8184qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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5
[SID99495826]
EC50 3.237Late stage results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for AHR activators [AID493060, Type: confirmatory]aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003]
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6
[SID14723599]
Potency 4.4668qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504466, Type: confirmatory]ATAD5 protein [Homo sapiens] [gi:116283940]
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7
[SID14723599]
IC50 5.17Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate [AID651559, Type: confirmatory]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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8
[SID14723599]
IC50 8.84Dose response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using Nedd8 Protein Substrate [AID624322, Type: confirmatory]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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9
[SID14723599]
Potency 12.5893qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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10
[SID14723599]
Potency 12.5893qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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11
[SID14723599]
Potency 15.1014qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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12
[SID14723599]
Potency 19.9526qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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13
[SID14723599]
EC50 42.24Luminescence Cell-Based Dose Response HTS to Identify Activators of Luciferase Translation or Activity in H4 Neuroglioblastoma Cells [AID2002, Type: confirmatory]
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14
[SID14723599]
Screen for Chemicals that Shorten Yeast Lifespan [AID804, Type: screening]
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15
[SID112296]
NCI Yeast Anticancer Drug Screen. Data for the rad52 strain [AID147, Type: other]
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16
[SID112296]
NCI Yeast Anticancer Drug Screen. Data for the rad50EPP+ strain [AID151, Type: other]
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17
[SID14723599]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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18
[SID14723599]
Screen for Chemicals that Shorten Yeast Lifespan, Dose response [AID849, Type: confirmatory]
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19
[SID112296]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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20
[SID112296]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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