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benzamidine (CID 2332) - Compound BioActivity Data
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BioActivity Outcomes:
Active(65)
 
 
Inactive(594)
 
 
Inconclusive(7)
 
 
Unspecified(20)
 
 
Top Targets:
Tryp SPc(61)
 
 
 
 
7TM GPCR Srx(20)
 
 
7TM GPCR Srsx(12)
 
 
p450(9)
 
 
Pyr redox dim(6)
 
 
BioAssay Types:
Screening(344)
 
 
 
Confirmatory(225)
 
 
 
 
 
Literature(91)
 
 
 
 
BioActivity Types:
Potency(184)
 
 
 
 
Ki(53)
 
 
 
IC50(14)
 
 
Kd(1)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 570    Data Row: 686   Total Pages: 35   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103186665]
Ki 0.031In vitro binding affinity by measuring the inhibition of bovine trypsin [AID215059, Type: Literature]Cationic trypsin [gi:205371855]
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2
[SID103186665]
Ki 0.031Inhibitory Activity against bovine trypsin [AID215198, Type: Literature]Cationic trypsin [gi:205371855]
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3
[SID103186665]
Ki 0.2Inhibitory concentration against human Coagulation factor Xa (fXa) [AID52164, Type: Literature]
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4
[SID103186665]
Ki 0.3In vitro binding affinity by measuring the inhibition of human thrombin [AID211004, Type: Literature]
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5
[SID103186665]
Ki 0.3Inhibitory Activity against human thrombin [AID211185, Type: Literature]
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6
[SID103186665]
Ki 0.41Binding affinity was evaluated against Coagulation factor X [AID51847, Type: Literature]
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7
[SID103186665]
Ki 1.24Binding affinity against human thrombin [AID211033, Type: Literature]Prothrombin [gi:135807]
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8
[SID46392813]
Ki 16.4Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, T190p Streptomyces Griseus Trypsin In Complex With Benzamidine [gi:34810494]
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9
[SID46392813]
Ki 16.4Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, T190p Streptomyces Griseus Trypsin In Complex With Benzamidine [gi:34810494]
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10
[SID103186665]
Ki 18.4Binding affinity against bovine trypsin [AID214878, Type: Literature]Cationic trypsin [gi:205371855]
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11
[SID46391647]
Ki 18.4Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Bovine Pancreas Beta-Trypsin In Complex With Benzamidine [gi:4699733]
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12
[SID46391647]
Ki 18.4Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Bovine Pancreas Beta-Trypsin In Complex With Benzamidine [gi:4699733]
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13
[SID53812740]
Kd 20Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Robotically Harvested Trypsin Complexed With Benzamidine Containing Polypeptide Mediated Crystal Contacts [gi:145579752]
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14
[SID103186665]
Ki 20Inhibitory concentration against bovine trypsin [AID228433, Type: Literature]Cationic trypsin [gi:205371855]
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15
[SID46391623]
Ki 21Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Structural Basis For Selectivity Of A Small Molecule, S1- Binding, Sub-Micromolar Inhibitor Of Urokinase Type Plasminogen Activator [gi:157838404]
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16
[SID46391623]
Ki 21Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Structural Basis For Selectivity Of A Small Molecule, S1- Binding, Sub-Micromolar Inhibitor Of Urokinase Type Plasminogen Activator [gi:157838404]
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17
[SID46392090]
Ki 22Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Structure Of Human Trypsin Iv (Brain Trypsin) [gi:20149993]
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18
[SID46392090]
Ki 22Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Structure Of Human Trypsin Iv (Brain Trypsin) [gi:20149993]
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19
[SID46392252]
Ki 32.2Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Benzamidine In Complex With Rat Trypsin Mutant X99rt [gi:27573668]
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20
[SID46392252]
Ki 32.2Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB [AID977610, Type: Literature]Chain A, Benzamidine In Complex With Rat Trypsin Mutant X99rt [gi:27573668]
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