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benefin (CID 2319) - Compound BioActivity Data
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BioActivity Outcomes:
Active(16)
 
 
Inactive(247)
 
 
Inconclusive(31)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
 
NR LBD AR(16)
 
 
NR LBD TR(12)
 
 
 
 
NR LBD VDR(11)
 
 
BioAssay Types:
Confirmatory(223)
 
 
 
 
Summary(48)
 
 
 
 
Literature(14)
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(257)
 
 
 
 
IC50(12)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 196    Data Row: 297   Total Pages: 15   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123091375]
IC50 1.5Antimicrobial activity against Toxoplasma gondii RH infected in HFF cells by plaque assay [AID522805, Type: Literature]
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2
[SID123091375]
IC50 3.7Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235V mutation infected in HFF cells by plaque assay [AID522813, Type: Literature]
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3
[SID123091375]
IC50 4.6Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235L mutation infected in HFF cells by plaque assay [AID522811, Type: Literature]
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4
[SID144211091]
Potency-Replicate_1 6.859qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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5
[SID123091375]
IC50 7.4Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin S6I mutation infected in HFF cells by plaque assay [AID522807, Type: Literature]
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6
[SID123091375]
IC50 9.3Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235T mutation infected in HFF cells by plaque assay [AID522812, Type: Literature]
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7
[SID144211091]
Ratio Potency (uM) 10.2626qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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8
[SID123091375]
IC50 12Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243C mutation infected in HFF cells by plaque assay [AID522815, Type: Literature]
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9
[SID123091375]
IC50 15.2Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin H28Q mutation infected in HFF cells by plaque assay [AID522809, Type: Literature]
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10
[SID123091375]
IC50 15.7Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin F24H mutation infected in HFF cells by plaque assay [AID522808, Type: Literature]
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11
[SID123091375]
IC50 18.8Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin V4L mutation infected in HFF cells by plaque assay [AID522806, Type: Literature]
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12
[SID123091375]
IC50 21.7Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243S mutation infected in HFF cells by plaque assay [AID522816, Type: Literature]
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13
[SID123091375]
IC50 22.9Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin T239I mutation infected in HFF cells by plaque assay [AID522814, Type: Literature]
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14
[SID123091375]
IC50 27.7Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin L136F mutation infected in HFF cells by plaque assay [AID522810, Type: Literature]
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15
[SID144211091]
Potency-Replicate_1 54.4827qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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16
[SID144209468]
TR Potency (uM) 67.0154qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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17
[SID26753695]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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18
[SID123091375]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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19
[SID123091375]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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20
[SID26747725]
Potency 15.8489qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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