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BioActivity Data for Compound Barbital (CID 2294)

BioActivity Outcomes:
Active(1)
 
 
Inactive(210)
 
 
Inconclusive(9)
 
 
Unspecified(21)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD TR(5)
 
 
NR LBD VDR(5)
 
 
 
BioAssay Types:
Confirmatory(127)
 
 
 
Literature(82)
 
 
 
 
Summary(24)
 
 
 
Screening(7)
 
 
BioAssay Categories:
In vitro(1)
 
 
In vivo(1)
 
 
Biochemical(1)
 
 
Toxicity(6)
 
 
ADME(7)
 
 
BioActivity Types:
Potency(139)
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 175    Data Row: 241   Total Pages: 13   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID48415603]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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2
[SID103165760]
Aqueous solubility [AID19262, Type: Literature]
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3
[SID103165760]
Compound is evaluated for ionization constant log k [AID24211, Type: Literature]
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4
[SID103165760]
pKa value is evaluated [AID26320, Type: Literature]
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5
[SID103165760]
Negative log of molar concentration (-log ED50) required to reduce cell division by 50% in Arbacia egg [AID38914, Type: Literature]
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6
[SID103165760]
Negative log of minimum effective dose (moles per kilogram) in rabbits (hypnotic) [AID167610, Type: Literature]
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7
[SID103165760]
Negative log of molar concentration (-log C) required to produce 50% inhibition of oxygen (oxygen uptake) on rat brain respiration in vitro [AID169097, Type: Literature]
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8
[SID103165760]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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9
[SID103165760]
Permeability coefficient in human skin [AID311367, Type: Literature]
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10
[SID103165760]
Binding affinity to beta cyclodextrin [AID346025, Type: Literature]
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11
[SID29215357]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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12
[SID103165760]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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13
[SID103165760]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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14
[SID103165760]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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15
[SID103165760]
Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset [AID588220, Type: Literature]
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16
[SID103165760]
In-vivo plasma to lung partition coefficients of the compound, logP(lung) in rat [AID603953, Type: Literature]
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17
[SID103165760]
Induction of hypnotic activity in rat [AID1145374, Type: Literature]
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18
[SID103165760]
Induction of hypnotic activity in rabbit [AID1145372, Type: Literature]
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19
[SID103165760]
Inhibition of Arbacia egg cell division [AID1130945, Type: Literature]
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20
[SID103165760]
Hypnotic activity in rabbit [AID1130944, Type: Literature]
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