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BioActivity Data for Compound azobenzene (CID 2272)

BioActivity Outcomes:
Active(9)
 
 
Inactive(554)
 
 
Inconclusive(101)
 
 
Unspecified(22)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
NR LBD ER(18)
 
 
 
 
NR LBD AR(18)
 
 
NR LBD TR(16)
 
 
 
NR LBD VDR(13)
 
 
 
BioAssay Types:
Confirmatory(385)
 
 
 
 
Summary(52)
 
 
 
Literature(12)
 
 
 
Screening(4)
 
 
BioAssay Categories:
In vitro(3)
 
 
 
In vivo(2)
 
 
Biochemical(4)
 
 
Toxicity(62)
 
 
 
 
 
ADME(4)
 
 
Cell-based(5)
 
 
 
Organism-base..(2)
 
 
BioActivity Types:
Potency(386)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 340    Data Row: 686   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17390028]
Potency 31.6228Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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2
[SID144208656]
Potency-Replicate_1 49.4975qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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3
[SID17390028]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_7, Type: other]
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4
[SID48413252]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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5
[SID48413252]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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6
[SID17390028]
Cell Viability - Jurkat [AID426, Type: confirmatory]
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7
[SID17390028]
Cellular Toxicity (caspase-3) Jurkat [AID655, Type: confirmatory]
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8
[SID48413252]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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9
[SID48413252]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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10
[SID103247002]
Partition coefficient (logP) [AID23714, Type: Literature]
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11
[SID103247002]
Capacity ratio (log k'w) [AID23978, Type: Literature]
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12
[SID103247002]
Binding constant against bovine serum albumin [AID203473, Type: Literature]
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13
[SID103247002]
Inhibition of Testosterone-5 alpha-reductase activity at pH 7.4 from rat; B = no inhibition at the highest concentration tested (20 uM) [AID212927, Type: Literature]
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14
[SID103247002]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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15
[SID103247002]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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16
[SID103247002]
Percent inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase from rat testes microsomes at 100 uM [AID207276, Type: Literature]Steroid 17-alpha-hydroxylase/17,20 lyase [gi:117286]
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17
[SID103247002]
Percent inhibition of 17-alpha-hydroxylase/17,20 lyase of rat testes microsomes at 100 uM [AID2948, Type: Literature]Steroid 17-alpha-hydroxylase/17,20 lyase [gi:117286]
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18
[SID8149758]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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19
[SID8149758]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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20
[SID8149758]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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