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STK176486 (CID 2258395) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(7)
 
 
Top Targets:
DSPc(2)
 
 
PTPc(1)
 
 
HSPA1-2 6-8-l..(1)
 
 
RNase H(1)
 
 
NR LBD NGFI-B(1)
 
 
BioAssay Types:
Screening(4)
 
 
Confirmatory(3)
 
 
BioActivity Types:
IC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID160644631]
Late stage assay for the probe development effort to identify transcriptional activators of heat shock protein 70 (Hsp70). Luminescence-based-cell-based high-throughput dose response assay for Hsp70 activators [AID651950, Type: other]Heat shock 70kDa protein 1A [Homo sapiens] [gi:12803275]
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2
[SID17466197]
IC50 MKP-3 in vitro HTS assay [AID425, Type: confirmatory]dual specificity protein phosphatase 6 [Rattus norvegicus] [gi:16758752]
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3
[SID17466197]
IC50 HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target [AID521, Type: confirmatory]tyrosine-protein phosphatase non-receptor type 7 isoform 2 [Homo sapiens] [gi:18375660]
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4
[SID17466197]
Fluorescence Polarization Screen Assay for Bcl-B Phenotype Converters [AID1240, Type: screening]nuclear receptor subfamily 4 group A member 1 isoform 1 [Homo sapiens] [gi:27894344]
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5
[SID8101006]
HIV-1 RNase H Inhibition [AID372, Type: screening]Chain A, Solution Structure Of The Rnase H Domain Of The Hiv-1 Reverse Transcriptase In The Presence Of Magnesium [gi:28949057]
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6
[SID17466197]
IC50 High Throughput Screening Assay for Hsp70 Inhibitors [AID583, Type: confirmatory]heat shock 70kDa protein 1A [Homo sapiens] [gi:123271505]
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7
[SID17466197]
High Throughput Screen for Inhibitors of ER Stress-induced Cell Death [AID1010, Type: screening]
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8
[SID17466197]
HTS Colorimetric assay for the identification of compounds that inhibit VHR1 [AID1992, Type: screening]dual specificity protein phosphatase 3 [Homo sapiens] [gi:4758208]
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