Bookmark and Share
AGN-PC-03OZJ2 (CID 22416235) - Compound BioActivity Data
.
BioActivity Outcomes:
Probe(1)
 
 
Active(79)
 
 
Inactive(379)
 
 
Inconclusive(22)
 
 
Unspecified(12)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
 
7TM GPCR Srsx(15)
 
 
 
Peptidase C48(8)
 
 
 
APOBEC C(6)
 
 
 
PMI typeI(6)
 
 
 
 
BioAssay Types:
Screening(323)
 
 
 
 
Confirmatory(137)
 
 
 
 
 
Literature(25)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(103)
 
 
 
 
 
IC50(28)
 
 
 
 
 
AC50(2)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 450    Data Row: 493   Total Pages: 25   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID57287553]
Summary - Compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. [AID1545, Type: summary]MPI protein [Homo sapiens] [gi:16878311]
View
2
[SID57287553]
IC50_Mean 0.792SAR assay for compounds that inhibit PHOSPHO1 [AID1666, Type: confirmatory]phosphoethanolamine/phosphocholine phosphatase isoform 1 [Homo sapiens] [gi:219689097]
View
3
[SID85285422]
IC50_Mean 1.03Confirmation assay for inhibitors of Trypanosoma brucei hexokinase 1-Analogue-first series [AID2230, Type: confirmatory]hexokinase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:70832125]
View
4
[SID85147390]
Potency 1.0621qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
5
[SID85147390]
Potency 1.122qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
View
6
[SID57287553]
IC50_Mean 1.25Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. [AID1535, Type: confirmatory]MPI protein [Homo sapiens] [gi:16878311]
View
7
[SID131285785]
IC50 1.3Inhibition of human purified phosphomannose isomerase [AID597374, Type: Literature]Mannose-6-phosphate isomerase [gi:462567]
View
8
[SID85147390]
AC50_uM 1.81Rtt109/Vps75 Measured in Biochemical System Using Plate Reader - 2106-01_Inhibitor_Dose_CherryPick_Activity [AID588764, Type: confirmatory]hypothetical protein CaO19.6625 [Candida albicans SC5314] [gi:68488893]
View
9
[SID85147390]
AC50_uM 1.81Rtt109/Vps75 Measured in Biochemical System Using Plate Reader - 2106-01_Inhibitor_Dose_CherryPick_Activity [AID588764, Type: confirmatory]hypothetical protein CaO19.7491 [Candida albicans SC5314] [gi:68474550]
View
10
[SID85147390]
Potency 1.8356qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
11
[SID85147390]
Potency 2.0596qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
12
[SID85147390]
Potency 4.1475Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
View
13
[SID85147390]
IC50 4.592Fluorescence-based cell-based high throughput dose response assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID651553, Type: confirmatory]caspase recruitment domain family, member 15 [Homo sapiens] [gi:119603173]
View
14
[SID85147390]
IC50 4.592Fluorescence-based cell-based high throughput dose response assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) [AID651553, Type: confirmatory]receptor-interacting serine/threonine-protein kinase 2 [Homo sapiens] [gi:4506537]
View
15
[SID85147390]
Potency 5.2213Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
16
[SID85147390]
IC50 5.796Counterscreen for inhibitors of TLR9-MyD88 binding: Luminescence-based cell-based high throughput dose response assay to identify cytotoxic compounds using TLR9-MyD88 CHO cells [AID588339, Type: confirmatory]
View
17
[SID85147390]
Potency 6.7456qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase [AID485367, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei] [gi:72386991]
View
18
[SID85147390]
Potency 7.0795qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
View
19
[SID85147390]
IC50_Mean 8.82Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay [AID504719, Type: confirmatory]DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] [gi:13399304]
View
20
[SID85147390]
Potency 8.9125qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
View