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Ammonia (CID 222) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inconclusive(2)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD TR(2)
 
 
BioAssay Types:
Literature(11)
 
 
 
 
BioActivity Types:
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 11    Data Row: 11   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103760905]
Inhibition of N-terminal His6-tagged Trypanosoma brucei CTPS assessed as conversion of UTP to CTP at 5.67 mM by continuous spectrophotometric assay [AID613857, Type: Literature]
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2
[SID103760905]
Inhibition of N-terminal His6-tagged Trypanosoma brucei CTPS assessed as conversion of UTP to CTP at 494.32 mM at pH 7.3 by continuous spectrophotometric assay [AID613858, Type: Literature]
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3
[SID103760905]
Inhibition of TRbeta-mediated PEPCK1 gene expression in human HepG2 cells at 10 uM after 24 hrs by RT-PCR analysis [AID677156, Type: Literature]Thyroid hormone receptor beta [gi:586092]
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4
[SID103760905]
Inhibition of TRbeta-mediated MMP11 gene expression in human HepG2 cells at 10 uM after 24 hrs by RT-PCR analysis [AID677157, Type: Literature]Thyroid hormone receptor beta [gi:586092]
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5
[SID103760905]
Ki 1400Activity of Escherichia coli CTPS assessed as conversion of UTP to CTP at pH 7.3 by continuous spectrophotometric assay [AID613859, Type: Literature]
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6
[SID103760905]
Ki 5700Activity of N-terminal His6-tagged Trypanosoma brucei CTPS assessed as conversion of UTP to CTP at pH 7.3 by continuous spectrophotometric assay [AID614224, Type: Literature]
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7
[SID103760905]
Ratio of Kcat for Escherichia coli CTPS to Kcat for N-terminal His6-tagged Trypanosoma brucei CTPS assessed as conversion of UTP to CTP by continuous spectrophotometric assay [AID613860, Type: Literature]
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8
[SID103760905]
Ratio of Kcat to Km for N-terminal His6-tagged Trypanosoma brucei CTPS assessed as conversion of UTP to CTP by continuous spectrophotometric assay [AID613861, Type: Literature]
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9
[SID103760905]
Ratio of Kcat to Km for Escherichia coli CTPS assessed as conversion of UTP to CTP by continuous spectrophotometric assay [AID613862, Type: Literature]
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10
[SID103760905]
Binding affinity at heteropentameric Nicotinic acetylcholine receptor alpha4-beta2 subtype using [3H]bungarotoxin as radioligand; Not determined [AID146636, Type: Literature]
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11
[SID103760905]
Binding affinity at homopentameric Nicotinic acetylcholine receptor alpha-7 subtype using [3H]S-(-)-nicotine as radioligand; Not determined [AID147084, Type: Literature]
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