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BioActivity Data for Compound Antipyrine (CID 2206)

BioActivity Outcomes:
Active(8)
 
 
Inactive(973)
 
 
Inconclusive(43)
 
 
Unspecified(462)
 
 
Top Targets:
7tm 4(60)
 
 
 
NR LBD PPAR(29)
 
 
 
p450(25)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD AR(24)
 
 
 
 
BioAssay Types:
Confirmatory(621)
 
 
 
 
 
Screening(293)
 
 
 
Literature(231)
 
 
 
 
Summary(72)
 
 
 
BioAssay Categories:
In vitro(13)
 
 
 
In vivo(29)
 
 
 
Biochemical(93)
 
 
 
Toxicity(64)
 
 
 
 
ADME(101)
 
 
Cell-based(109)
 
 
 
 
Organism-base..(9)
 
 
 
BioActivity Types:
Potency(517)
 
 
 
 
 
IC50(124)
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1091    Data Row: 1486   Total Pages: 75   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56320742]
Potency 5.0119qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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2
[SID56320742]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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3
[SID56320742]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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4
[SID103188539]
Antipyretic activity against IL-1beta-induced hyperthermia in rat assessed as change in rectal temperature at 100 mg/kg, icv measured after 2 hrs [AID604519, Type: Literature]
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5
[SID103188539]
Antinociceptive activity in rat assessed as suppression of carrageenan-induced nociception in right hind paw at 100 mg/kg, po measured after 1 hr [AID604523, Type: Literature]
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6
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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7
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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8
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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9
[SID8149206]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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10
[SID8149206]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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11
[SID8149206]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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12
[SID8149206]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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13
[SID11112159]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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14
[SID103188539]
Partition coefficient (logP) (HPLC) [AID29421, Type: Literature]
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15
[SID103188539]
HPLC capacity factor (k') [AID29423, Type: Literature]
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16
[SID103188539]
Fraction absorbed after oral administration in humans [AID29844, Type: Literature]
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17
[SID103188539]
Estimation of fraction absorbed (Fa) in the human intestine using biosensor technology. [AID29845, Type: Literature]
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18
[SID103188539]
Volume of distribution in man (IV dose) [AID29925, Type: Literature]
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19
[SID103188539]
Binding constant against human serum albumin (HSA) [AID91481, Type: Literature]
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20
[SID103188539]
Binding to POPC (palmitoyl-oleolyl-phosphatidyl-choline) liposomes using biosensor system [AID156202, Type: Literature]
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