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Antipyrine (CID 2206) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(958)
 
 
Inconclusive(46)
 
 
Unspecified(425)
 
 
Top Targets:
7TM GPCR Srx(31)
 
 
 
NR LBD PPAR(29)
 
 
 
7TM GPCR Srsx(29)
 
 
 
p450(25)
 
 
 
NR LBD ER(25)
 
 
 
BioAssay Types:
Confirmatory(618)
 
 
 
 
 
Screening(284)
 
 
 
Literature(200)
 
 
 
 
Summary(72)
 
 
 
BioActivity Types:
Potency(517)
 
 
 
 
 
IC50(124)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1042    Data Row: 1437   Total Pages: 72   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56320742]
Potency 5.0119qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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2
[SID56320742]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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3
[SID56320742]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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4
[SID103188539]
Antipyretic activity against IL-1beta-induced hyperthermia in rat assessed as change in rectal temperature at 100 mg/kg, icv measured after 2 hrs [AID604519, Type: Literature]
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5
[SID103188539]
Antinociceptive activity in rat assessed as suppression of carrageenan-induced nociception in right hind paw at 100 mg/kg, po measured after 1 hr [AID604523, Type: Literature]
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6
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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7
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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8
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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9
[SID8149206]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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10
[SID8149206]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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11
[SID8149206]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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12
[SID8149206]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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13
[SID103188539]
pKa value of the compound. (extrapolated value) [AID26400, Type: Literature]
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14
[SID103188539]
HPLC capacity factor (k) [AID27575, Type: Literature]
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15
[SID103188539]
Partition coefficient (logP) [AID27580, Type: Literature]
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16
[SID103188539]
Fraction ionized (pH 7.4) [AID28233, Type: Literature]
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17
[SID103188539]
Unbound fraction (plasma) [AID28235, Type: Literature]
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18
[SID103188539]
Unbound fraction (tissues) [AID28236, Type: Literature]
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19
[SID103188539]
Apparent permeability coefficient (Papp) (Caco-2 cell monolayer) [AID28392, Type: Literature]
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20
[SID103188539]
Cellular permeability (Pc) (Caco-2 cell monolayer) [AID28399, Type: Literature]
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