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Antipyrine (CID 2206) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(962)
 
 
Inconclusive(43)
 
 
Unspecified(448)
 
 
Top Targets:
7TM GPCR Srx(30)
 
 
 
7TM GPCR Srsx(29)
 
 
 
NR LBD PPAR(29)
 
 
 
NR LBD ER(25)
 
 
 
p450(25)
 
 
 
BioAssay Types:
Confirmatory(618)
 
 
 
 
 
Screening(285)
 
 
 
Literature(223)
 
 
 
 
Summary(72)
 
 
 
BioActivity Types:
Potency(517)
 
 
 
 
 
IC50(124)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1066    Data Row: 1461   Total Pages: 74   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56320742]
Potency 5.0119qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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2
[SID56320742]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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3
[SID103188539]
Antipyretic activity against IL-1beta-induced hyperthermia in rat assessed as change in rectal temperature at 100 mg/kg, icv measured after 2 hrs [AID604519, Type: Literature]
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4
[SID103188539]
Antinociceptive activity in rat assessed as suppression of carrageenan-induced nociception in right hind paw at 100 mg/kg, po measured after 1 hr [AID604523, Type: Literature]
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5
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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6
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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7
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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8
[SID56320742]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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9
[SID11112159]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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10
[SID103188539]
Unbound fraction (plasma) [AID7783, Type: Literature]
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11
[SID103188539]
Observed volume of distribution [AID8002, Type: Literature]
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12
[SID103188539]
Percent of the drug absorbed after administration to humans was determined [AID15120, Type: Literature]
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13
[SID103188539]
Calculated partition coefficient (clogP) [AID15711, Type: Literature]
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14
[SID103188539]
Percent of drug absorbed by human intestine after oral administration [AID18847, Type: Literature]
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15
[SID103188539]
GOF value represents multisets of log P data [AID18861, Type: Literature]
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16
[SID103188539]
Partition coefficient (logD7.4) [AID19424, Type: Literature]
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17
[SID103188539]
Effective permeability measured in human. [AID21264, Type: Literature]
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18
[SID103188539]
In vitro clearance in dog in 1000000 cells [AID21849, Type: Literature]
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19
[SID103188539]
In vitro clearance in human in 1000000 cells [AID21851, Type: Literature]
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20
[SID103188539]
In vitro clearance in rat in 1000000 cells [AID21852, Type: Literature]
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