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Antipyrine (CID 2206) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(961)
 
 
Inconclusive(43)
 
 
Unspecified(425)
 
 
Top Targets:
7TM GPCR Srx(31)
 
 
 
NR LBD PPAR(29)
 
 
 
7TM GPCR Srsx(29)
 
 
 
p450(25)
 
 
 
NR LBD ER(25)
 
 
 
BioAssay Types:
Confirmatory(618)
 
 
 
 
 
Screening(284)
 
 
 
Literature(200)
 
 
 
 
Summary(72)
 
 
 
BioActivity Types:
Potency(517)
 
 
 
 
 
IC50(124)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1042    Data Row: 1437   Total Pages: 72   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56320742]
Potency 5.0119qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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2
[SID56320742]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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3
[SID103188539]
Antipyretic activity against IL-1beta-induced hyperthermia in rat assessed as change in rectal temperature at 100 mg/kg, icv measured after 2 hrs [AID604519, Type: Literature]
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4
[SID103188539]
Antinociceptive activity in rat assessed as suppression of carrageenan-induced nociception in right hind paw at 100 mg/kg, po measured after 1 hr [AID604523, Type: Literature]
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5
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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6
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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7
[SID56320742]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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8
[SID48414294]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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9
[SID103188539]
Lipophilicity, log D of the compound [AID453203, Type: Literature]
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10
[SID103188539]
Permeability in human skin after 48 hrs by Franz cell permeability assay [AID453204, Type: Literature]
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11
[SID103188539]
Permeability across human Caco-2 cells [AID455986, Type: Literature]
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12
[SID103188539]
Fraction unbound in human plasma [AID444050, Type: Literature]
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13
[SID103188539]
Total clearance in human [AID444051, Type: Literature]
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14
[SID103188539]
Hepatic clearance in human [AID444052, Type: Literature]
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15
[SID103188539]
Renal clearance in human [AID444053, Type: Literature]
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16
[SID103188539]
Oral bioavailability in human [AID444054, Type: Literature]
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17
[SID103188539]
Fraction absorbed in human [AID444055, Type: Literature]
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18
[SID103188539]
Fraction escaping gut-wall elimination in human [AID444056, Type: Literature]
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19
[SID103188539]
Fraction escaping hepatic elimination in human [AID444057, Type: Literature]
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20
[SID103188539]
Volume of distribution at steady state in human [AID444058, Type: Literature]
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