ST090871 (CID 2201779) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(28)
 
 
Inactive(409)
 
 
Inconclusive(43)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(11)
 
 
alkPPc(10)
 
 
Bcl-2 like(10)
 
 
G-alpha(6)
 
 
 
RGS RGS4(6)
 
 
 
 
BioAssay Types:
Screening(291)
 
 
 
 
Confirmatory(176)
 
 
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(131)
 
 
 
 
 
IC50(30)
 
 
EC50(10)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 481    Data Row: 481   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24822998]
Potency 4.2284qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation in Primary Screen [AID602199, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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2
[SID24822998]
Potency 4.2284qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation in Primary Screen [AID602199, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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3
[SID24822998]
Potency 4.2284qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation in Primary Screen [AID602199, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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4
[SID24822998]
Potency 4.2284qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation in Primary Screen [AID602199, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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5
[SID24822998]
Potency 5.8048qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]
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6
[SID24822998]
Potency 7.9433qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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7
[SID24822998]
Potency 10qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]NPSR1 gene product [Homo sapiens] [gi:46395496]
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8
[SID24822998]
Potency 10qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]NPSR1 gene product [Homo sapiens] [gi:46395496]
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9
[SID24822998]
Potency 10qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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10
[SID24822998]
EC50 10.4Dose response confirmation of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID489024, Type: confirmatory]
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11
[SID24822998]
Potency 11.2202qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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12
[SID24822998]
Potency 11.2202qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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13
[SID24822998]
Potency 11.2202Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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14
[SID24822998]
Potency 11.2202Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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15
[SID24822998]
Potency 11.2202Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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16
[SID24822998]
Potency 11.2202Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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17
[SID24822998]
Potency 11.5821qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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18
[SID24822998]
Potency 14.1254qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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19
[SID24822998]
Potency 14.1254qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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20
[SID24822998]
Potency 14.581A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
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21
[SID24822998]
Potency 17.7828qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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22
[SID24822998]
Potency 25.1189qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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23
[SID24822998]
Potency 25.1189qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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24
[SID24822998]
 Primary cell-based high-throughput screening assay for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4) [AID463165, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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25
[SID24822998]
 Primary cell-based high-throughput screening assay for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4) [AID463165, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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26
[SID24822998]
 Primary cell-based high-throughput screening assay for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4) [AID463165, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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27
[SID24822998]
 Validation assay for identification of compounds that inhibit the regulator of G-protein signaling 4 (RGS4) [AID492999, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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28
[SID24822998]
 Validation assay for identification of compounds that inhibit the regulator of G-protein signaling 4 (RGS4) [AID492999, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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29
[SID24822998]
 Validation assay for identification of compounds that inhibit the regulator of G-protein signaling 4 (RGS4) [AID492999, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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30
[SID24822998]
 Second counter screen for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay without carbachol activation [AID493001, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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31
[SID24822998]
 Second counter screen for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay without carbachol activation [AID493001, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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32
[SID24822998]
 Second counter screen for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay without carbachol activation [AID493001, Type: screening]RGS4 gene product [Homo sapiens] [gi:5032039]
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33
[SID24822998]
 HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]Ddit3 gene product [Mus musculus] [gi:160707929]
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34
[SID24822998]
 HTS assay for identification of inhibitors of TNF-a-specific NF-kB induction [AID1852, Type: other]TNF gene product [Homo sapiens] [gi:25952111]
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35
[SID24822998]
 HTS assay for identification of inhibitors of TNF-a-specific NF-kB induction [AID1852, Type: other]TNF gene product [Homo sapiens] [gi:25952111]
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36
[SID24822998]
 Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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37
[SID24822998]
 Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN. [AID2023, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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38
[SID24822998]
 Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) [AID652126, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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39
[SID24822998]
 Single concentration confirmation of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID463112, Type: screening]
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40
[SID24822998]
 384-well Z-Lyte format Hck-Nef inhibitor HTS run at the PMLSC [AID463187, Type: screening]
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41
[SID24822998]
 Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_SinglePoint_HTS_Activity [AID651661, Type: screening]
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42
[SID24822998]
 uHTS identification of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay [AID449763, Type: screening]
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43
[SID24822998]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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44
[SID24822998]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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45
[SID24822998]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
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46
[SID24822998]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
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47
[SID24822998]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
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48
[SID24822998]
 Primary cell-based high-throughput screening for identification of compounds that inhibit/block calcium-activated chloride channels (TMEM16A) [AID588511, Type: screening]Ano1 gene product [Mus musculus] [gi:334278898]
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49
[SID24822998]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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50
[SID24822998]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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