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4-hydroxy-6-(phenylamino)naphthalene-1-sulfonic acid (CID 219926) - Compound BioActivity Data
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BioActivity Outcomes:
Active(87)
 
 
Inactive(265)
 
 
Inconclusive(11)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(12)
 
 
7TM GPCR Srsx(11)
 
 
Troponin(8)
 
 
 
Hexokinase 2(6)
 
 
 
ABCC CFTR1(4)
 
 
BioAssay Types:
Screening(228)
 
 
 
Confirmatory(114)
 
 
 
 
 
Literature(10)
 
 
 
BioActivity Types:
Potency(85)
 
 
 
 
 
IC50(22)
 
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 316    Data Row: 364   Total Pages: 19   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID89852629]
Potency 0.0607qHTS for Inhibitors of WRN Helicase: BLM Helicase Counterscreen for WRN Inhibitors [AID720503, Type: confirmatory]Bloom syndrome protein isoform 1 [Homo sapiens] [gi:4557365]
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2
[SID89852629]
Potency 0.4294qHTS for Inhibitors of WRN Helicase: Confirmatory Assay for Cherry-picked Compounds. [AID720497, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
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3
[SID89852629]
Potency 0.5323qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds [AID720501, Type: Literature]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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4
[SID89852629]
IC50_Mean 0.58Dose response confirmation of uHTS inhibitor hits of SUMO1-mediated protein-protein interactions using a SUMO2 fluorescence resonance energy transfer selectivity assay [AID624384, Type: confirmatory]small ubiquitin-related modifier 2 isoform b precursor [Homo sapiens] [gi:54792071]
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5
[SID89852629]
Potency 0.6506qHTS for inhibitors of Phosphogylcerate Kinase: Hit Validation Screen [AID686980, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:115503961]
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6
[SID89852629]
Potency 0.6702qHTS for Inhibitors of Polymerase Iota: Confirmatory Assay for Cherry-picked Compounds [AID720496, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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7
[SID89852629]
IC50 0.72254TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID1053172, Type: confirmatory]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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8
[SID89852629]
IC50 0.72254TR-FRET-based biochemical high throughput dose response assay to identify inhibitors of HIV-1 LEDGF/p75 DNA Integration [AID1053172, Type: confirmatory]integrase, partial [Human immunodeficiency virus 1] [gi:2853980]
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9
[SID89852629]
Potency 0.7569qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds [AID720502, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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10
[SID89852629]
Potency 0.7943qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta isoform 1 [Homo sapiens] [gi:5729982]
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11
[SID89852629]
IC50_Mean 0.88Dose response confirmation of uHTS inhibitor hits of SUMO1-mediated protein-protein interactions using a fluorescence resonance energy transfer assay [AID624383, Type: confirmatory]SUMO-1 [Homo sapiens] [gi:1762973]
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12
[SID89852629]
Potency 0.9466qHTS for Inhibitors of WRN Helicase [AID651768, Type: confirmatory]WRN [Homo sapiens] [gi:3719421]
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13
[SID89852629]
IC50 0.953Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization [AID1053171, Type: confirmatory]integrase, partial [Human immunodeficiency virus 1] [gi:2853980]
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14
[SID89852629]
IC50 0.953Counterscreen for inhibitors of LEDGF/p75-dependent integration: TR-FRET-based biochemical high throughput dose response counterscreen assay to identify activators of HIV-1 Integrase multimerization [AID1053171, Type: confirmatory]lens epithelium-derived growth factor p75 [Homo sapiens] [gi:6708281]
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15
[SID89852629]
Potency 1.6944qHTS Assay to Find Inhibitors of Pin1: Hit Validation [AID624308, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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16
[SID89852629]
Potency 1.9953HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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17
[SID89852629]
Potency 2.2387qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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18
[SID89852629]
Potency 2.8184qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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19
[SID89852629]
Potency 2.8184qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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20
[SID89852629]
Potency 3.0131qHTS Assay to Find Inhibitors of Pin1: Hit Validation using Tamra Binding [AID624312, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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