1-phenylbutane-1,2-dione (CID 219605) - BioAssay Data Summary for Compound
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BioActivity Outcomes:
Active(4)
 
 
Top Targets:
Esterase lipa..(4)
 
 
BioAssay Types:
Literature(4)
 
 
BioActivity Types:
Ki(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 4   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134463147]
Ki 1.55Inhibition of human liver carboxylesterase1 using o-nitrophenyl acetate as substrate after 5 mins by spectrophotometry [AID612130, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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2
[SID134463147]
Ki 1.55Inhibition of human liver carboxylesterase1 using o-nitrophenyl acetate as substrate after 5 mins by spectrophotometry [AID612130, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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3
[SID134463147]
Ki 2.01Inhibition of human intestinal carboxylesterase assessed as hydrolysis of CPT-11 after 5 mins by HPLC [AID612137, Type: Literature]Cocaine esterase [gi:46576349]
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4
[SID134463147]
Ki 2.42Inhibition of human intestinal carboxylesterase using o-nitrophenyl acetate as substrate after 5 mins by spectrophotometry [AID612131, Type: Literature]Cocaine esterase [gi:46576349]
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5
[SID134463147]
Ki 12.5Inhibition of rabbit liver carboxylesterase using o-nitrophenyl acetate as substrate after for 5 mins by spectrophotometry [AID612132, Type: Literature]Liver carboxylesterase 1 [gi:51338757]
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