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BioActivity Data for Compound isostearic acid (CID 21859)

BioActivity Outcomes:
Active(10)
 
 
Inactive(100)
 
 
Inconclusive(30)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD AR(9)
 
 
 
NR LBD ER(9)
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD Fxr(6)
 
 
BioAssay Types:
Confirmatory(103)
 
 
 
 
Summary(29)
 
 
 
 
BioAssay Categories:
Toxicity(15)
 
 
 
BioActivity Types:
Potency(126)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 133    Data Row: 141   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144212593]
Potency-Replicate_1 10.9622qHTS assay to identify small molecule agonists of the RXR signaling pathway [AID1159527, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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2
[SID144212593]
Ratio Potency (uM) 12.2998qHTS assay to identify small molecule agonists of the RXR signaling pathway: Summary [AID1159531, Type: summary]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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3
[SID144212593]
TR Potency (uM) 13.6854qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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4
[SID144212593]
Potency-Replicate_1 24.5412qHTS assay to identify small molecule agonists of the AP-1 signaling pathway - cell viability counter screen [AID1159525, Type: confirmatory]
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5
[SID144212593]
Potency-Replicate_1 24.5412qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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6
[SID144212593]
Ratio Potency (uM) 29.7324qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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7
[SID26757811]
Potency 39.8107qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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8
[SID144212593]
Potency-Replicate_1 54.4827qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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9
[SID144212593]
Potency-Replicate_1 61.1306qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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10
[SID144212593]
Potency-Replicate_1 68.5896qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID1159520, Type: confirmatory]
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11
[SID26757811]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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12
[SID144212593]
Potency-Replicate_1 9.77qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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13
[SID144212593]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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14
[SID144212593]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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15
[SID144212593]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
16
[SID144212593]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
17
[SID144212593]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
18
[SID144212593]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
19
[SID144212593]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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20
[SID26757811]
Potency qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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