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Amsacrine (CID 2179) - Compound BioActivity Data
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BioActivity Outcomes:
Active(257)
 
 
Inactive(134)
 
 
Inconclusive(53)
 
 
Unspecified(251)
 
 
Top Targets:
p450(15)
 
 
 
 
TOP4c(9)
 
 
 
7tm 4(7)
 
 
 
 
Pyruvate Kina..(4)
 
 
Pyr redox dim(4)
 
 
BioAssay Types:
Literature(416)
 
 
 
 
 
Confirmatory(225)
 
 
 
 
BioActivity Types:
IC50(127)
 
 
 
 
Potency(116)
 
 
 
 
EC50(11)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 678    Data Row: 695   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103166066]
IC50 0.0006Inhibitory activity of compound for AA8 cells to reduce cell density by 50% (exposed to compound for 4 hours) [AID45745, Type: Literature]
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2
[SID103166066]
IC50 0.004The compound was tested for the cytotoxicity DC-3F cell lines [AID53603, Type: Literature]
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3
[SID103166066]
IC50 0.0051Antiproliferative activity against human HL60 cells after 72 hrs by trypan blue test [AID317175, Type: Literature]
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4
[SID103166066]
IC50 0.006Growth inhibition in human HL60 cells after 72 hrs by trypan blue assay [AID576613, Type: Literature]
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5
[SID103166066]
IC50 0.012Growth inhibition in human HeLa cells after 72 hrs by trypan blue assay [AID576615, Type: Literature]
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6
[SID103166066]
IC50 0.012Antiproliferative activity against human HeLa cells after 72 hrs by trypan blue test [AID317174, Type: Literature]
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7
[SID103166066]
IC50 0.012Inhibitory activity against Lewis lung carcinoma cells [AID100108, Type: Literature]
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8
[SID103166066]
IC50 0.012Inhibitory concentration against Murine Lewis lung carcinoma (LLC) cell proliferation [AID100239, Type: Literature]
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9
[SID103166066]
IC50 0.012Inhibitory concentration required to reduce Lewis lung carcinoma cell number to 50% of control cultures [AID100240, Type: Literature]
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10
[SID103166066]
IC50 0.012Inhibitory activity of tested against Murine Lewis lung carcinoma [AID103106, Type: Literature]
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11
[SID103166066]
IC50 0.012In vitro cell growth inhibitory activity against wild type P388 murine leukemia cell line (P388/W) [AID150522, Type: Literature]
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12
[SID103166066]
IC50 0.02Cytotoxicity against human Jurkat cells by Hoechst test [AID365818, Type: Literature]
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13
[SID103166066]
IC50 0.02Inhibitory activity against P388 murine leukemia cells [AID150659, Type: Literature]
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14
[SID103166066]
IC50 0.02Inhibitory activity against Murine p38 leukemia [AID150664, Type: Literature]
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15
[SID103166066]
IC50 0.02Inhibitory concentration to reduce cell number to 50% of Murine P388 leukemia cell culture [AID150670, Type: Literature]
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16
[SID103166066]
IC50 0.02Inhibitory concentration required to reduce murine p388 leukemia cell number to 50% of control cultures [AID150673, Type: Literature]
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17
[SID103166066]
IC50 0.021In vitro cytotoxicity against human leukemic HL-60 cell line. [AID81631, Type: Literature]
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18
[SID103166066]
IC50 0.023Cytotoxicity against human K562 cells after 5 days by XTT assay [AID312292, Type: Literature]
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19
[SID103166066]
ID50 0.03Concentration for inhibiting the growth of P-388 cells by 50% over 3 days was determined [AID150694, Type: Literature]
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20
[SID103166066]
IC50 0.03Inhibitory activity against A549 cell line using MTT assay(Wild type p53) [AID8681, Type: Literature]
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