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cyclohexane-1,2-dicarboxylic acid bis(oxiranylmethyl) ester (CID 21660) - Compound BioActivity Data
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BioActivity Outcomes:
Active(128)
 
 
Inactive(137)
 
 
Inconclusive(142)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
 
Summary(24)
 
 
 
 
Literature(1)
 
 
BioActivity Types:
Potency(193)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 237    Data Row: 410   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144207203]
Potency-Replicate_1 0.7704qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144207203]
Potency-Replicate_1 8.6437qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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3
[SID144207203]
Potency-Replicate_1 9.6984qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID144207203]
Ratio Potency (uM) 24.3613qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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5
[SID144207203]
Potency-Replicate_1 27.3338qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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6
[SID17389480]
Potency 31.6228qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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7
[SID144207203]
Ratio Potency (uM) 36.7869qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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8
[SID17389480]
Potency 39.8107Cell Viability - LYMP1-002 - Assay at 40 hr [AID994, Type: confirmatory]
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9
[SID17389480]
Potency 39.8107Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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10
[SID17389480]
Potency 39.8107Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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11
[SID17389480]
Potency 42.1632qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID144207203]
Potency-Replicate_1 48.6071qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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13
[SID144207203]
Potency-Replicate_1 48.6071qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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14
[SID144207203]
Potency-Replicate_1 49.0561qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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15
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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16
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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17
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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18
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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19
[SID144207203]
Ratio Potency (uM) 50.5087qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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20
[SID144207203]
Potency-Replicate_1 54.5381qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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21
[SID144207203]
Potency-Replicate_1 55.0418qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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22
[SID144207203]
ATAD5 Potency (uM) 66.0744qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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23
[SID17389480]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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24
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_72, Type: other]
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25
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_73, Type: other]
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26
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_75, Type: other]
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27
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_76, Type: other]
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28
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_65, Type: other]
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29
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_66, Type: other]
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30
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_67, Type: other]
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31
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_69, Type: other]
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32
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_70, Type: other]
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33
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_59, Type: other]
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34
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_60, Type: other]
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35
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_61, Type: other]
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36
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_63, Type: other]
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37
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_64, Type: other]
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38
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_53, Type: other]
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39
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_54, Type: other]
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40
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_56, Type: other]
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41
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_57, Type: other]
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42
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_58, Type: other]
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43
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_47, Type: other]
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44
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_48, Type: other]
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45
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_49, Type: other]
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46
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_50, Type: other]
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47
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_51, Type: other]
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48
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_36, Type: other]
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49
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_37, Type: other]
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50
[SID17389480]
Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_38, Type: other]
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