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cyclohexane-1,2-dicarboxylic acid bis(oxiranylmethyl) ester (CID 21660) - Compound BioActivity Data
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BioActivity Outcomes:
Active(126)
 
 
Inactive(153)
 
 
Inconclusive(129)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD ER(9)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
 
Summary(24)
 
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(194)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 237    Data Row: 411   Total Pages: 21   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144207203]
Potency-Replicate_1 0.7704qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144207203]
Potency-Replicate_1 8.6437qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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3
[SID144207203]
Potency-Replicate_1 9.6984qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID144207203]
Ratio Potency (uM) 24.3613qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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5
[SID144207203]
Potency-Replicate_1 27.3338qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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6
[SID17389480]
Potency 31.6228qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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7
[SID144207203]
Ratio Potency (uM) 36.7869qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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8
[SID17389480]
Potency 39.8107Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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9
[SID17389480]
Potency 39.8107Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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10
[SID17389480]
Potency 39.8107Cell Viability - LYMP1-002 - Assay at 40 hr [AID994, Type: confirmatory]
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11
[SID17389480]
Potency 42.1632qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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12
[SID144207203]
Potency-Replicate_1 48.6071qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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13
[SID144207203]
Potency-Replicate_1 48.6071qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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14
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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15
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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16
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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17
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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18
[SID144207203]
Ratio Potency (uM) 50.5087qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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19
[SID144207203]
Potency-Replicate_1 54.5381qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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20
[SID144207203]
ATAD5 Potency (uM) 66.0744qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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