cyclohexane-1,2-dicarboxylic acid bis(oxiranylmethyl) ester (CID 21660) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(115)
 
 
Inactive(88)
 
 
Inconclusive(109)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
 
NR LBD TR(4)
 
 
 
P53(3)
 
 
 
 
NR LBD ROR li..(3)
 
 
NR LBD VDR(2)
 
 
BioAssay Types:
Confirmatory(141)
 
 
 
 
Literature(1)
 
 
BioActivity Types:
Potency(105)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 145    Data Row: 315   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389480]
Potency 31.6228qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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2
[SID17389480]
Potency 31.6228qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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3
[SID17389480]
Potency 31.6228qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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4
[SID17389480]
Potency 31.6228qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
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5
[SID17389480]
Potency 39.8107Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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6
[SID17389480]
Potency 39.8107Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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7
[SID17389480]
Potency 39.8107Cell Viability - LYMP1-002 - Assay at 40 hr [AID994, Type: confirmatory]
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8
[SID17389480]
Potency 42.1632qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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9
[SID17389480]
Potency 42.1632qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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10
[SID17389480]
Potency 42.1632qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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11
[SID17389480]
Potency 42.1632qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]NFE2L2 gene product [Homo sapiens] [gi:20149576]
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12
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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13
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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14
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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15
[SID17389480]
Potency 50.1187Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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16
[SID17389480]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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17
[SID17389480]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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18
[SID17389480]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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19
[SID17389480]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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20
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_1, Type: other]
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21
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_5, Type: other]
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22
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_10, Type: other]
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23
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_7, Type: other]
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24
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_8, Type: other]
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25
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_14, Type: other]
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26
[SID17389480]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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27
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_20, Type: other]
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28
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_21, Type: other]
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29
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_22, Type: other]
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30
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_23, Type: other]
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31
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_24, Type: other]
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32
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_33, Type: other]
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33
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_38, Type: other]
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34
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_36, Type: other]
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35
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_43, Type: other]
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36
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_45, Type: other]
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37
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_48, Type: other]
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38
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_50, Type: other]
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39
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_58, Type: other]
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40
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_60, Type: other]
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41
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_61, Type: other]
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42
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_63, Type: other]
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43
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_64, Type: other]
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44
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_65, Type: other]
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45
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_67, Type: other]
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46
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_68, Type: other]
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47
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_73, Type: other]
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48
[SID17389480]
 Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_75, Type: other]
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49
[SID17389480]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_4, Type: other]
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50
[SID17389480]
 Caspase-3/7 Activation Profiling of Human Lymphoblast Cell Lines [AID588813_5, Type: other]
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