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raspberry ketone (CID 21648) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(84)
 
 
Inconclusive(6)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD AR(9)
 
 
 
 
NR LBD PPAR(8)
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD VDR(4)
 
 
 
BioAssay Types:
Confirmatory(63)
 
 
 
 
Summary(24)
 
 
Literature(5)
 
 
 
BioActivity Types:
Potency(80)
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 95    Data Row: 95   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103323362]
IC50 100In vitro cell growth inhibitory activity against K562 human chronic myelogenous leukemia cell line [AID94792, Type: confirmatory]
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2
[SID103323362]
IC50 252Antagonist activity at AR in human MDA-kb2 cells co-transfected with MMTV-luc assessed as decrease in DHT-induced luciferase activity by reporter gene assay [AID473864, Type: Literature]Androgen receptor [gi:113830]
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3
[SID103323362]
Drug level in Wistar rat blood at 10 g/kg [AID473867, Type: Literature]
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4
[SID103323362]
Induction of NGF production in rat C6 cells at 20 uM after 24 hrs by ELISA relative to untreated control [AID589667, Type: Literature]
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5
[SID103323362]
Cytotoxicity against rat C6 cells assessed as viable cells at 20 uM after 24 hrs by MTT assay [AID589668, Type: Literature]
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6
[SID144211776]
Potency-Replicate_1 54.4827qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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7
[SID144211776]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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8
[SID144211776]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID144211776]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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10
[SID144211776]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743241, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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11
[SID144211776]
qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743242, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
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12
[SID144211776]
Ratio Potency (uM) qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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13
[SID144211776]
Potency-Replicate_1 qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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14
[SID144211776]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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15
[SID144211776]
ATAD5 Potency (uM) qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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16
[SID144211776]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720719, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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17
[SID144211776]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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18
[SID144211776]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway [AID720691, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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19
[SID144211776]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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20
[SID144211776]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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