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2-[(2-bromobenzyl)oxy]benzoic acid (CID 2160985) - Compound BioActivity Data
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BioActivity Outcomes:
Probe(1)
 
 
Active(13)
 
 
Inactive(686)
 
 
Inconclusive(4)
 
 
Unspecified(6)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(17)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(467)
 
 
 
 
 
Confirmatory(212)
 
 
 
 
 
Literature(11)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(142)
 
 
 
 
IC50(39)
 
 
EC50(26)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 635    Data Row: 710   Total Pages: 36   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID57578338]
Project utilizing multiplex HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases [AID1772, Type: summary]ras protein, partial [Homo sapiens] [gi:190938]
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2
[SID57578338]
EC50_MICROM 0.103Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID1334, Type: confirmatory]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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3
[SID57578338]
EC50_MICROM 0.109Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID1335, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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4
[SID57578338]
EC50_MICROM 0.151Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID1340, Type: confirmatory]Rac1 protein [Homo sapiens] [gi:8574038]
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5
[SID24838021]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID757, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
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6
[SID24838021]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant [AID764, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
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7
[SID24838021]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID761, Type: screening]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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8
[SID24838021]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID760, Type: screening]Ras-related protein Rab-2A [gi:46577642]
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9
[SID24838021]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID758, Type: screening]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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10
[SID24838021]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
View
11
[SID24838021]
Early assessment of compound solubility in 1x PBS - Set 2 [AID624321, Type: other]
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12
[SID24838021]
Early assessment of compound solubility in aqueous buffer - Set 2 [AID624323, Type: other]
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13
[SID24838021]
Parallel artificial membrane permeability assay at pH 7.4 [AID624339, Type: other]
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14
[SID24838021]
Primary biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase [AID1527, Type: screening]metallo beta-lactamase [Pseudomonas aeruginosa] [gi:7381449]
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15
[SID24838021]
Plasma Stability Mouse - Set 2 [AID624419, Type: other]
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16
[SID24838021]
Plasma Stability Human - 2 [AID624420, Type: other]
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17
[SID24838021]
Mouse hepatic microsome stability - Set 2 [AID624451, Type: screening]
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18
[SID24838021]
Human hepatic microsome stability-Set 2 [AID624452, Type: screening]
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19
[SID24838021]
Early assessment of compound stability in 1x PBS - Set 2 [AID624456, Type: other]
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20
[SID24838021]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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