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4-amino-3-hydroxybutyric acid (CID 2149) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(223)
 
 
Inconclusive(24)
 
 
Unspecified(16)
 
 
Top Targets:
NR LBD ER(7)
 
 
 
NR LBD AR(7)
 
 
NR LBD TR(5)
 
 
P53(4)
 
 
p450(4)
 
 
BioAssay Types:
Confirmatory(128)
 
 
 
 
Literature(68)
 
 
 
Summary(15)
 
 
Screening(6)
 
 
BioActivity Types:
Potency(138)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 199    Data Row: 264   Total Pages: 14   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144204928]
Potency-Replicate_1 16.7855qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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2
[SID8149878]
Screen for compounds that induce the human heat shock transcriptional response (HSEluc) [AID1611, Type: other]
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3
[SID8149878]
Screen for compounds that increase glutamate transport activity in MN-1 cell line (GluUPTAKE) [AID1612, Type: other]
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4
[SID8149878]
Screen for compounds that inhibit protein aggregation formed by mutant SOD1 (GFPSOD1) [AID1613, Type: other]
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5
[SID8149878]
Screen for compounds that reduce polyglutamine (polyQ) inclusions in nerve growth factor (NGF)-treated PC12 cells (GFPQ80) [AID1614, Type: other]
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6
[SID8149878]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH) [AID1616, Type: other]
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7
[SID103303557]
Affinity of compound towards the carnitine/acylcarnitine translocase was determined by monitoring the efflux of [14C]L-carnitine from isolated rat heart mitochondria [AID49192, Type: Literature]
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8
[SID103303557]
Virtual screen for compounds with anticonvulsant activity [AID227699, Type: Literature]
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9
[SID26748669]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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10
[SID8149878]
Assay to identify inhibitors of polyglutamine-induced caspase-3 activation (CASP3) [AID1583, Type: other]
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11
[SID8149878]
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubU) [AID1593, Type: other]
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12
[SID8149878]
Screen for compounds that correct neuronal dysfunction without cell death as induced by the expression of polyglutamine-expanded, N-terminal huntingtin in C. elegans mechanosensory neurons (HDELENEU) [AID1599, Type: other]
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13
[SID8149878]
Screen for compounds that selectively inhibit cytochrome c release from purified mitochondria (CytoCRel) [AID1603, Type: other]
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14
[SID8149878]
Screen for compounds that inhibit polyglutamine induced protein aggregation (AGREG) [AID1604, Type: other]
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15
[SID8149878]
Screening of compounds showing protective effect against cell death induced by familial amyotrophic lateral sclerosis (FALS)-linked mutantsuperoxide dismutase 1 (SOD1) (ALSOD1) [AID1605, Type: other]
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16
[SID103303557]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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17
[SID103303557]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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18
[SID26748669]
Potency Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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19
[SID144204928]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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20
[SID144204928]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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