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MLS000530082 (CID 2136878) - Compound BioActivity Data
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BioActivity Outcomes:
Active(79)
 
 
Inactive(688)
 
 
Inconclusive(40)
 
 
Unspecified(10)
 
 
Top Targets:
7TM GPCR Srx(25)
 
 
 
7TM GPCR Srsx(19)
 
 
 
Bcl-2 like(13)
 
 
 
alkPPc(12)
 
 
Death TRAILR..(12)
 
 
 
 
BioAssay Types:
Screening(566)
 
 
 
 
 
Confirmatory(229)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(150)
 
 
 
 
 
IC50(45)
 
 
 
EC50(21)
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 731    Data Row: 817   Total Pages: 41   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14733521]
Potency 0.4147Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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2
[SID14733521]
EC50 0.921134Image-based HTS for Selective Agonists of GPR55 [AID1961, Type: confirmatory]G-protein coupled receptor 55 [Homo sapiens] [gi:33695107]
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3
[SID14733521]
AbsAC40_uM 1.23High Content Cell-Based Imaging Primary HTS to Identify Small Molecules Involved in X-Chromosome Reactivation and Reprogramming Measured in Cell-Based System Using Imaging - 7015-01_Activator_Dose_CherryPick_Activity [AID743394, Type: confirmatory]
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4
[SID14733521]
EC50 2.58Counterscreen for Fluorescence in GFP-Spectra Wavelengths Caused By Cell-Permeable Autofluorescent Compounds [AID2124, Type: confirmatory]
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5
[SID14733521]
EC50 2.89HCS for Compounds that Up-Regulate Insulin Promoter Activity in MIN6 Cells [AID1625, Type: confirmatory]
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6
[SID14733521]
EC50_Mean 2.91Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 [AID504549, Type: confirmatory]neurotensin receptor type 1 [Homo sapiens] [gi:110611243]
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7
[SID14733521]
Potency 3.2643qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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8
[SID14733521]
AbsAC40_uM 3.67High Content Cell-Based Imaging Primary HTS to Identify autofluorescent compounds using cells not inducing Measured in Cell-Based System Using Imaging - 7015-02_Activator_Dose_CherryPick_Activity [AID743396, Type: confirmatory]
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9
[SID14733521]
Potency 5.1735qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID14733521]
EC50 5.844High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression - Dose Response [AID1045, Type: confirmatory]
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11
[SID14733521]
EC50 5.913High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor - Dose Response [AID1047, Type: confirmatory]
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12
[SID124384791]
EC50_Mean 6.02SAR analysis of small molecule NTR1 agonists in a image based NTR2 selectivity assay [AID588495, Type: confirmatory]neurotensin receptor type 2 [Homo sapiens] [gi:6912538]
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13
[SID14733521]
Potency 7.0795VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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14
[SID124384791]
EC50_Mean 7.24SAR analysis of small molecule Agonists NTR1 in a image based assay set 3 [AID602356, Type: confirmatory]neurotensin receptor type 1 [Homo sapiens] [gi:110611243]
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15
[SID126531621]
EC50_Mean 7.28SAR analysis of small molecule NTR1 agonists in a image based NTR2 selectivity assay set 2 [AID602334, Type: confirmatory]neurotensin receptor type 2 [Homo sapiens] [gi:6912538]
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16
[SID126531621]
EC50_Mean 7.42SAR analysis of small molecule Agonists NTR1 in a image based assay set 3 [AID602356, Type: confirmatory]neurotensin receptor type 1 [Homo sapiens] [gi:110611243]
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17
[SID124384791]
EC50_Mean 9.39SAR analysis of small molecule NTR1 agonists in a image based NTR2 selectivity assay set 2 [AID602334, Type: confirmatory]neurotensin receptor type 2 [Homo sapiens] [gi:6912538]
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18
[SID124384791]
EC50_Mean 9.82SAR analysis of small molecule NTR1 agonists in a image based GPR35 selectivity assay [AID588503, Type: confirmatory]G-protein coupled receptor 35 [Homo sapiens] [gi:30526188]
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19
[SID14733521]
Potency 11.2202qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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20
[SID14733521]
Potency 31.6228Inhibitors of USP1/UAF1: Primary Screen [AID743255, Type: confirmatory]USP1 protein, partial [Homo sapiens] [gi:118600387]
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