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CHEMBL1914582 (CID 21337669) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Unspecified(2)
 
 
BioAssay Types:
Literature(7)
 
 
 
BioActivity Types:
EC50(2)
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 7    Data Row: 7   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136925406]
IC50 16.4Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution assay [AID630382, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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2
[SID136925406]
EC50 45.9Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay [AID630439, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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3
[SID136925406]
Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of GPR35 antagonist SPB05142 [AID630441, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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4
[SID136925406]
Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of 64 uM GPR35 antagonist SPB05142 [AID630442, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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5
[SID136925406]
Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay relative to zaprinast [AID630387, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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6
[SID136925406]
EC50 50Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay [AID630386, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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7
[SID136925406]
Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay relative to zaprinast [AID630381, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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