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famoxadon (CID 213032) - Compound BioActivity Data
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BioActivity Outcomes:
Active(46)
 
 
Inactive(38)
 
 
Inconclusive(44)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
NR LBD Fxr(6)
 
 
 
 
NR LBD VDR(6)
 
 
 
BioAssay Types:
Confirmatory(89)
 
 
 
 
Summary(24)
 
 
 
 
Literature(9)
 
 
 
 
BioActivity Types:
Potency(107)
 
 
 
 
IC50(4)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 123    Data Row: 131   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134451477]
IC50 0.00362Inhibition of pig heart succinate-cytochrome c reductase (Electron transport protein complex 2/3) assessed as increase of cytochrome c by spectrophotometer [AID611596, Type: Literature]
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2
[SID134451477]
IC50 0.00478Non-competitive inhibition of pig heart succinate-cytochrome c reductase (Electron transport protein complex 2/3) using cytochrome c as substrate by Line-weaverBurk plot analysis [AID611599, Type: Literature]
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3
[SID134451477]
IC50 0.04821Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate in absence of lauryl maltoside by Line-weaverBurk plot analysis [AID611600, Type: Literature]
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4
[SID134451477]
Ki 0.05143Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate by Line-weaverBurk plot analysis [AID611602, Type: Literature]
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5
[SID134451477]
IC50 0.14202Competitive inhibition of pig heart Cytochrome b-c1 complex using DBH2 as substrate in presence of lauryl maltoside by Line-weaverBurk plot analysis [AID611601, Type: Literature]
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6
[SID144211461]
Potency-Replicate_1 0.615qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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7
[SID144211461]
Potency-Replicate_1 0.7743qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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8
[SID144211461]
Potency-Replicate_1 0.8688qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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9
[SID144211461]
Ratio Potency (uM) 1.0129qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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10
[SID144211461]
Potency-Replicate_1 1.0937qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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11
[SID144211461]
Potency-Replicate_1 1.9449qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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12
[SID144211461]
TR Potency (uM) 3.08249qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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13
[SID144211461]
Potency-Replicate_1 3.8806qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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14
[SID144211461]
Ratio Potency (uM) 4.1902qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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15
[SID134451477]
Km 4.4678Activity of pig heart succinate-cytochrome c reductase (Electron transport protein complex 2/3) using cytochrome c as substrate by Line-weaverBurk plot analysis [AID611606, Type: Literature]
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16
[SID50113103]
Potency 5.0119qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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17
[SID144211461]
Potency-Replicate_1 5.4815qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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18
[SID144211461]
Potency-Replicate_1 5.5271qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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19
[SID144211461]
AR Potency (uM) 5.91882qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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20
[SID144211461]
Potency-Replicate_1 8.7598qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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