Bookmark and Share
MLS000067308 (CID 2064400) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(32)
 
 
Inactive(689)
 
 
Inconclusive(34)
 
 
Unspecified(24)
 
 
Top Targets:
7tm 4(43)
 
 
 
ABCC CFTR1(17)
 
 
 
 
Chemokine CXC(16)
 
 
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
BioAssay Types:
Screening(519)
 
 
 
 
 
Confirmatory(237)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(146)
 
 
 
 
 
IC50(73)
 
 
 
 
 
EC50(9)
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 682    Data Row: 779   Total Pages: 39   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID16953363]
IC50_Mean 0.628Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a PAF-induced IL8 counterscreen [AID624343, Type: confirmatory]interleukin-8 precursor [Homo sapiens] [gi:10834978]
View
2
[SID144089005]
IC50_CF-PAF_Mean 4SAR analysis of molecule cystic fibrosis induced NFkb Inhibitors in a panel assay [AID651592_8, Type: confirmatory]interleukin-8 precursor [Homo sapiens] [gi:10834978]
View
3
[SID16953363]
AC50_uM 8.842HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity [AID540270, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
View
4
[SID16953363]
EC50 9.357High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor - Dose Response [AID1047, Type: confirmatory]
View
5
[SID16953363]
EC50 13.507High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression - Dose Response [AID1045, Type: confirmatory]
View
6
[SID16953363]
AC50_uM 18.141Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
View
7
[SID16953363]
Potency 22.3872qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
View
8
[SID16953363]
IC50 24.187Dose response confirmation of uHTS hits for small molecule modulators of myocardial damage [AID588779, Type: confirmatory]
View
9
[SID16953363]
Potency 39.8107qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
10
[SID16953363]
Potency 50.1187qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
View
11
[SID144089005]
IC50_CF-PAF_Mean 66SAR analysis of molecule cystic fibrosis induced NFkb Inhibitors in a panel assay [AID651592_15, Type: confirmatory]interleukin-8 precursor [Homo sapiens] [gi:10834978]
View
12
[SID16953363]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
13
[SID16953363]
uHTS identification of small molecule inhibitors of tim23-1 yeast via a luminescent assay [AID463212, Type: screening]TPA: protein transporter TIM23 [Saccharomyces cerevisiae S288c] [gi:285814664]
View
14
[SID16953363]
Single concentration confirmation of small molecule inhibitors of tim23-1 yeast via a luminescent assay [AID463218, Type: screening]TPA: protein transporter TIM23 [Saccharomyces cerevisiae S288c] [gi:285814664]
View
15
[SID16953363]
Primary cell-based high-throughput screening assay for potentiators or agonists of NPY-Y2 [AID1359, Type: screening]neuropeptide Y receptor type 2 [Homo sapiens] [gi:4505447]
View
16
[SID16953363]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
View
17
[SID16953363]
uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay [AID588850, Type: screening]cystic fibrosis transmembrane conductance regulator [Homo sapiens] [gi:90421313]
View
18
[SID16953363]
IC50_CF-PAF_Mean Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a panel assay [AID624344_1, Type: confirmatory]cystic fibrosis transmembrane conductance regulator [Homo sapiens] [gi:90421313]
View
19
[SID16953363]
Primary cell-based high-throughput screening assay for potentiators or agonists of NPY-Y1 [AID1304, Type: screening]neuropeptide Y receptor type 1 [Homo sapiens] [gi:4505445]
View
20
[SID16953363]
Single concentration confirmation of uHTS hits for cystic fibrosis induced NFkb Inhibitors in a fluoresence assay [AID602472, Type: screening]cystic fibrosis transmembrane conductance regulator [Homo sapiens] [gi:90421313]
View