Bookmark and Share
AC1M0YGG (CID 2059132) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(101)
 
 
Inactive(563)
 
 
Inconclusive(50)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(38)
 
 
 
Bcl-2 like(15)
 
 
 
 
alkPPc(10)
 
 
KCNQ channel(8)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(443)
 
 
 
 
Confirmatory(231)
 
 
 
 
 
Literature(13)
 
 
BioActivity Types:
Potency(156)
 
 
 
 
 
IC50(40)
 
 
 
 
EC50(16)
 
 
 
 
AC50(10)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 647    Data Row: 715   Total Pages: 36   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24781837]
Potency 0.1585Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504848, Type: confirmatory]
View
2
[SID24781837]
Absolute IC50 (CHOP) 0.3CHOP dose-response primary assay [AID504322, Type: confirmatory]DNA damage-inducible transcript 3 protein [Mus musculus] [gi:160707929]
View
3
[SID24781837]
Potency 0.3162Confirmation screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504850, Type: confirmatory]
View
4
[SID24781837]
Potency 0.4109A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
View
5
[SID24781837]
Potency 0.5174qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
6
[SID24781837]
Absolute IC50 (XBP1) 0.55XBP1 DR counterscreen for CHOP [AID504313, Type: confirmatory]XBP1 [Homo sapiens] [gi:47678753]
View
7
[SID24781837]
AC50_uM 0.5793Luminescence Cell-Based Dose Retest to Confirm Inhibitors of Beta Cell Apoptosis [AID449756, Type: confirmatory]
View
8
[SID24781837]
Potency 0.5848qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation in HepG2 cytotox [AID588382, Type: confirmatory]
View
9
[SID24781837]
Potency 0.6513qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
View
10
[SID24781837]
AC50_uM 0.6717ATP-based Luminescence in the Absence of Cytokines Measured in Cell-Based System Using Plate Reader - 2061-06_Inhibitor_Dose_CherryPick [AID463229, Type: confirmatory]
View
11
[SID24781837]
Potency 0.7308qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
View
12
[SID24781837]
Potency 0.8913qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
View
13
[SID24781837]
Potency 0.8913qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
View
14
[SID24781837]
Potency 0.92qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
15
[SID24781837]
Potency 0.9952qHTS Assay for Inhibitors of Hepatitis C Virus (HCV): Confirmation Assay for Cherry-picked Compounds [AID720575, Type: confirmatory]hepatitis C virus polyprotein [Hepatitis C virus] [gi:295901482]
View
16
[SID24781837]
Potency 1.0323qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation using a Beta-Lactamase Assay [AID602202, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View
17
[SID24781837]
Potency 1.4058qHTS Assay for Inhibitors of Hepatitis C Virus (HCV): Cytotoxicity Counterscreen for Cherry-picked Compounds [AID720576, Type: confirmatory]
View
18
[SID24781837]
Potency 1.7783qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
View
19
[SID24781837]
Potency 1.9953qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction [AID1461, Type: confirmatory]neuropeptide S receptor isoform A [Homo sapiens] [gi:46395496]
View
20
[SID24781837]
Potency 1.9953qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation using a Fluorescein Assay [AID602200, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View