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STK575322 (CID 2037119) - Compound BioActivity Data
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BioActivity Outcomes:
Active(40)
 
 
Inactive(721)
 
 
Inconclusive(13)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(30)
 
 
 
TRP 2(25)
 
 
 
7TM GPCR Srsx(18)
 
 
 
alkPPc(12)
 
 
Bcl-2 like(11)
 
 
BioAssay Types:
Screening(521)
 
 
 
 
Confirmatory(218)
 
 
 
 
 
Literature(13)
 
 
BioActivity Types:
Potency(144)
 
 
 
 
 
IC50(49)
 
 
 
 
EC50(19)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 708    Data Row: 775   Total Pages: 39   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14743393]
EC50 0.596Confirmation dose response assay for compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID434937, Type: confirmatory]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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2
[SID14743393]
Potency 2.8184qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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3
[SID87348216]
EC50 2.953Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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4
[SID87348216]
EC50 2.953Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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5
[SID87348216]
EC50 3.961Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization [AID588411, Type: confirmatory]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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6
[SID14743393]
Potency 8.2753Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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7
[SID14743393]
Potency 10qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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8
[SID14743393]
Potency 11.2202qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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9
[SID14743393]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID14743393]
Potency 20.5962qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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11
[SID87348216]
IC50 27.3Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay [AID602368, Type: confirmatory]PSMD14 protein [Homo sapiens] [gi:16306916]
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12
[SID87348216]
IC50 97.7Dose Response validation of uHTS RPN11 inhibitor hits using a Thrombin Fluorescence Polarization assay [AID602369, Type: confirmatory]TPA: prothrombin [Bos taurus] [gi:296479639]
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13
[SID14743393]
Primary cell-based screen for identification of compounds that activate transient receptor potential cation channel C4 (TRPC4). [AID2237, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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14
[SID14743393]
Confirmatory screen for identification of compounds that activate transient receptor potential cation channel C4 (TRPC4) [AID2426, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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15
[SID14743393]
Second counter screen for compounds that activate transient receptor potential cation channel C4 (TRPC4). [AID434977, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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16
[SID87348216]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504326, Type: screening]delta-type opioid receptor [Homo sapiens] [gi:63477962]
View
17
[SID14743393]
Second specificity screen against TRPC4 for compounds that inhibit transient receptor potential cation channel C6 (TRPC6) [AID2776, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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18
[SID14743393]
Specificity screen against TRPC4 for compounds that inhibit transient receptor potential cation channel C6 (TRPC6) [AID2777, Type: screening]alternatively spliced Trp4 [Mus musculus] [gi:2935630]
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19
[SID87348216]
Luminescence-based cell-based high throughput confirmation assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504904, Type: screening]delta-type opioid receptor [Homo sapiens] [gi:63477962]
View
20
[SID14743393]
Antagonist of Human D 1 Dopamine Receptor: qHTS [AID504652, Type: screening]D(1A) dopamine receptor [Homo sapiens] [gi:4503383]
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