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alpha-Tocopherol (CID 20353) - Compound BioActivity Data
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BioActivity Outcomes:
Active(11)
 
 
Inactive(195)
 
 
Inconclusive(47)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD AR(14)
 
 
 
NR LBD ER(14)
 
 
 
NR LBD PPAR(10)
 
 
 
NR LBD GR(8)
 
 
 
NR LBD TR(6)
 
 
 
BioAssay Types:
Confirmatory(140)
 
 
 
 
Literature(77)
 
 
 
 
 
Summary(39)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(170)
 
 
 
 
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 136    Data Row: 258   Total Pages: 13   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103283478]
IC50 10Inhibition of mouse 4T1 cells adhesion to gelatinous matrix protein-coated surface after 60 mins by ELISA [AID448010, Type: Literature]
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2
[SID50112815]
Potency 11.9955Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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3
[SID144206109]
Potency-Replicate_1 23.7101qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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4
[SID144206109]
Potency-Replicate_1 26.8325qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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5
[SID50112815]
Potency 35.4813Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein [Homo sapiens] [gi:118600387]
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6
[SID50112815]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_57, Type: Literature]
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7
[SID103283478]
Inhibition of mouse 4T1 cells adhesion to collagen 4 at 5 to 100 uM after 60 mins by ELISA [AID448615, Type: Literature]
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8
[SID103283478]
Inhibition of mouse 4T1 cells adhesion to fibronectin at 5 to 100 uM after 60 mins by ELISA [AID448616, Type: Literature]
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9
[SID103283478]
Inhibition of mouse 4T1 cells adhesion to laminin at 5 to 100 uM after 60 mins by ELISA [AID448617, Type: Literature]
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10
[SID103283478]
Inhibition of mouse 4T1 cells adhesion to vitronectin at 5 to 100 uM after 60 mins by ELISA [AID448618, Type: Literature]
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11
[SID50112815]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_26, Type: Literature]
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12
[SID103283478]
IC50 368Compound was tested for antiproliferative activity against human breast cancer cell line MCF-7 in MTT assay [AID103204, Type: Literature]
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13
[SID50112815]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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14
[SID103283478]
Inhibition of mouse 4T1 cells adhesion to gelatinous matrix protein-coated surface at 10 uM after 60 mins by ELISA [AID448011, Type: Literature]
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15
[SID103283478]
IC50 Inhibition of human MCF7 cells adhesion to gelatinous matrix protein-coated surface after 60 mins by ELISA [AID448012, Type: Literature]
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16
[SID103283478]
IC50 Inhibition of human SK-BR-3 cells adhesion to gelatinous matrix protein-coated surface after 60 mins by ELISA [AID448013, Type: Literature]
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17
[SID144207766]
Potency-Replicate_1 6.1815qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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18
[SID144207766]
Potency-Replicate_1 7.8509qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID144206109]
Potency-Replicate_1 8.4852qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID144207766]
Potency-Replicate_1 9.8837qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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