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2,2',4'-trichloroacetophenone (CID 20250) - Compound BioActivity Data
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BioActivity Outcomes:
Active(279)
 
 
Inactive(174)
 
 
Inconclusive(121)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD ER(23)
 
 
 
NR LBD PPAR(23)
 
 
 
 
NR LBD AR(23)
 
 
 
NR LBD GR(14)
 
 
 
 
NR LBD TR(13)
 
 
 
 
BioAssay Types:
Confirmatory(336)
 
 
 
 
Summary(63)
 
 
 
 
Screening(4)
 
 
Literature(1)
 
 
BioActivity Types:
Potency(348)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 248    Data Row: 577   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389431]
Potency 0.1585qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID144206797]
Potency-Replicate_1 0.6682qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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3
[SID144206797]
Potency-Replicate_1 0.9439qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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4
[SID144206797]
Potency-Replicate_1 1.0591qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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5
[SID144206797]
Potency-Replicate_1 1.3333qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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6
[SID144206797]
Potency-Replicate_1 1.496qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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7
[SID144207010]
Potency-Replicate_1 1.7229qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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8
[SID17389431]
Potency 1.9953Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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9
[SID144207010]
Potency-Replicate_1 2.4337qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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10
[SID17389431]
Potency 2.5119Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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11
[SID17389431]
Potency 2.5119Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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12
[SID144207010]
Potency-Replicate_1 2.7306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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13
[SID17389431]
Potency 3.1623Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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14
[SID17389431]
Potency 3.1623Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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15
[SID17389431]
Potency 3.1623Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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16
[SID144207010]
Potency-Replicate_1 3.4376qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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17
[SID144206797]
Potency 3.5481qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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18
[SID17389431]
Potency 3.7578qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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19
[SID17389431]
Potency 3.9811Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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20
[SID17389431]
Potency 3.9811Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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21
[SID144206797]
Potency-Replicate_1 4.2163qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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22
[SID144207010]
Potency-Replicate_1 4.3277qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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23
[SID144206797]
Ratio Potency (uM) 4.55268qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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24
[SID17389431]
Potency 5.0119qHTS Assay for Anthrax Lethal Toxin Internalization [AID912, Type: confirmatory]lethal factor [Bacillus anthracis str. A2012] [gi:21392848]
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25
[SID17389431]
Potency 5.0119Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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26
[SID17389431]
Potency 5.0119Cell Viability - LYMP2-014 [AID983, Type: confirmatory]
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27
[SID17389431]
Potency 5.0119Cell Viability - LYMP2-016 [AID984, Type: confirmatory]
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28
[SID17389431]
Potency 5.0119Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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29
[SID17389431]
Potency 5.0119Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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30
[SID170466727]
Ratio Potency (uM) 5.30763qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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31
[SID144206797]
Potency-Replicate_1 5.9557qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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32
[SID144206797]
Potency 5.9569qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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33
[SID144206797]
Potency-Replicate_1 6.007qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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34
[SID17389431]
Potency 6.3096Cell Viability - LYMP2-026 [AID989, Type: confirmatory]
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35
[SID17389431]
Potency 6.3096Cell Viability - LYMP2-009 [AID968, Type: confirmatory]
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36
[SID17389431]
Potency 6.3096Cell Viability - LYMP2-011 [AID969, Type: confirmatory]
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37
[SID17389431]
Potency 6.3096Cell Viability - LYMP2-023 [AID975, Type: confirmatory]
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38
[SID144206797]
Potency 6.3096qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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39
[SID17389431]
Potency 6.3096Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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40
[SID144206797]
Potency 6.6838qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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41
[SID17389431]
Potency 7.4978qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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42
[SID17389431]
Potency 7.9433MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Live Cells [AID955, Type: confirmatory]
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43
[SID17389431]
Potency 7.9433MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Dead Cells [AID960, Type: confirmatory]
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44
[SID17389431]
Potency 7.9433Cell Viability - LYMP2-025 [AID976, Type: confirmatory]
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45
[SID17389431]
Potency 7.9433Cell Viability - LYMP2-002 [AID977, Type: confirmatory]
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46
[SID17389431]
Potency 7.9433Cell Viability - LYMP2-006 [AID978, Type: confirmatory]
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47
[SID17389431]
Potency 7.9433Cell Viability - LYMP2-019 [AID973, Type: confirmatory]
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48
[SID17389431]
Potency 7.9433Cell Viability - LYMP2-013 [AID970, Type: confirmatory]
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49
[SID17389431]
Potency 7.9433Cell Viability - LYMP2-008 [AID980, Type: confirmatory]
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50
[SID170466727]
Potency-Replicate_1 8.412qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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