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BioActivity Data for Compound 2,2',4'-trichloroacetophenone (CID 20250)

BioActivity Outcomes:
Active(296)
 
 
Inactive(206)
 
 
Inconclusive(127)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(23)
 
 
 
 
NR LBD ER(23)
 
 
 
NR LBD AR(23)
 
 
 
NR LBD GR(14)
 
 
 
 
NR LBD TR(13)
 
 
 
 
BioAssay Types:
Confirmatory(373)
 
 
 
 
Summary(67)
 
 
 
 
Screening(17)
 
 
 
Literature(2)
 
 
BioAssay Categories:
Biochemical(2)
 
 
Toxicity(48)
 
 
 
 
 
Cell-based(30)
 
 
 
BioActivity Types:
Potency(367)
 
 
 
 
IC50(17)
 
 
 
AC50(6)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 293    Data Row: 632   Total Pages: 32   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389431]
Potency 0.1585qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID170466727]
IC50 0.35Decreased HeLa cell count-IC50 [AID1117347, Type: confirmatory]
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3
[SID170466727]
IC50 0.3728nuclear beta catenin stimulation in WNT3A conditioned C2C12 cells-IC50 [AID1117325, Type: confirmatory]
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4
[SID170466727]
IC50 0.514Increased HeLa cells with 2N DNA content-IC50 [AID1117349, Type: confirmatory]
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5
[SID170466727]
IC50 0.53012Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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6
[SID170466727]
IC50 0.541Increased chromatin condensation in HeLa cells-IC50 [AID1117350, Type: confirmatory]
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7
[SID144206797]
Potency-Replicate_1 0.6682qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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8
[SID144206797]
Potency-Replicate_1 0.9439qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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9
[SID144206797]
Potency-Replicate_1 1.0591qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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10
[SID170466727]
IC50 1.09834GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50 [AID1117339, Type: confirmatory]
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11
[SID170466727]
IC50 1.24875SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
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12
[SID144206797]
Potency-Replicate_1 1.3333qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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13
[SID144206797]
Potency-Replicate_1 1.496qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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14
[SID144207010]
Potency-Replicate_1 1.7229qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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15
[SID17389431]
Potency 1.9953Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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16
[SID170466727]
IC50 2.0651DLD-1 viability from Cell TiterGlo-IC50 [AID1117352, Type: confirmatory]
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17
[SID144207010]
Potency-Replicate_1 2.4337qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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18
[SID170466727]
IC50 2.4875VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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19
[SID17389431]
Potency 2.5119Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
View
20
[SID17389431]
Potency 2.5119Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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