Bookmark and Share
nitroxoline (CID 19910) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(174)
 
 
Inactive(763)
 
 
Inconclusive(129)
 
 
Unspecified(10)
 
 
Top Targets:
7TM GPCR Srsx(25)
 
 
 
 
7TM GPCR Srx(23)
 
 
NR LBD PPAR(14)
 
 
 
 
Bcl-2 like(11)
 
 
 
KCNQ channel(10)
 
 
 
BioAssay Types:
Screening(568)
 
 
 
 
Confirmatory(350)
 
 
 
 
 
Literature(99)
 
 
 
 
 
Summary(24)
 
 
 
 
BioActivity Types:
Potency(269)
 
 
 
 
 
IC50(51)
 
 
 
 
 
EC50(33)
 
 
 
 
AC50(10)
 
 
Ki(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 869    Data Row: 1076   Total Pages: 54   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124971549]
IC50 0.055Inhibition of human methionine aminopeptidase 2 [AID760045, Type: Literature]Methionine aminopeptidase 2 [gi:1703273]
View
2
[SID124971549]
IC50 0.06Inhibition of Burkholderia pseudomallei recombinant methionine aminopeptidase 1 using H-Met-Gly-Pro-7-amino-4-methylcoumarin hydrochloride as substrate measured for 10 mins by fluorescence assay in presence of human recombinant DPP4 [AID760047, Type: Literature]
View
3
[SID11532939]
EC50 0.161Fluorescence Cell-Based Retest of C. albicans Growth in the Presence of Fluconazole [AID2467, Type: confirmatory]
View
4
[SID170466124]
Ratio Potency (uM) 0.195689qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
View
5
[SID29216358]
Potency 0.2818qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
6
[SID11532939]
Potency 0.4467VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
7
[SID29216358]
Potency 0.5623VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
8
[SID11532939]
EC50_MICROM 0.607Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits [AID2745, Type: confirmatory]LAP4 [Saccharomyces cerevisiae] [gi:486173]
View
9
[SID11532939]
EC50 0.681Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole [AID2423, Type: confirmatory]heat shock protein 90 [Candida albicans] [gi:994798]
View
10
[SID11532939]
Potency 0.7079qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
11
[SID56423111]
EC50_MICROM 0.752Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits [AID2745, Type: confirmatory]LAP4 [Saccharomyces cerevisiae] [gi:486173]
View
12
[SID11532939]
IC50 0.79A counter screen for small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID2384, Type: confirmatory]
View
13
[SID11532939]
IC50 0.96A small molecule screen for inhibitors of the PhoP regulon in Salmonella typhi [AID1850, Type: confirmatory]
View
14
[SID11532939]
AC50_uM 0.996HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity [AID540270, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
View
15
[SID11532939]
AC50_uM 1.657Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
View
16
[SID56423111]
IC50 2.37A Counter Screen to identiry small molecule screen for inhibitors of the PhoP regulon in Salmonella Typhimurium [AID2401, Type: confirmatory]
View
17
[SID144205522]
Potency-Replicate_1 2.6603qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
18
[SID144205522]
Potency 2.6609qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
View
19
[SID56423111]
IC50 2.7A screen for inhibitors of the PhoP regulon in Salmonella Typhimurium using a modified counterscreen. [AID1981, Type: confirmatory]
View
20
[SID144205522]
Potency-Replicate_1 2.9849qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View