Acetazolamide (CID 1986) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(982)
 
 
Inactive(1255)
 
 
Inconclusive(66)
 
 
Unspecified(1865)
 
 
Top Targets:
alpha CA I II..(428)
 
 
 
alpha CA(173)
 
 
 
 
alpha CA XII..(97)
 
 
 
alpha CA IV X..(44)
 
 
 
alpha CA V(39)
 
 
 
BioAssay Types:
Literature(1429)
 
 
 
 
 
Confirmatory(568)
 
 
 
 
Screening(550)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Ki(698)
 
 
 
Potency(454)
 
 
 
 
IC50(319)
 
 
 
 
 
EC50(11)
 
 
Kd(9)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3822    Data Row: 4168   Total Pages: 84   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103164735]
Ki 0.0008Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive) [AID50175, Type: Literature]
View
2
[SID103164735]
Ki 0.0018Mean inhibitory constant towards human carbonic anhydrase V determined by spectrophotometric dansylamide binding assay [AID239287, Type: Literature]Carbonic anhydrase 5A, mitochondrial [gi:461680]
View
3
[SID103164735]
Ki 0.0025Inhibition of human carbonic anhydrase 7 [AID311030, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
4
[SID103164735]
Ki 0.0025Inhibition of human recombinant CA7 after 15 mins by CO2 hydration stopped flow assay [AID295293, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
5
[SID103164735]
Ki 0.0025Inhibition of human cloned CA7 by stopped-flow CO2 hydration method [AID272525, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
6
[SID103164735]
Ki 0.0025Inhibition of human CA7 by stopped-flow CO2 hydration assay [AID462277, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
7
[SID103164735]
Ki 0.0025Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration method [AID610544, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
8
[SID103164735]
Ki 0.0025Inhibition of human carbonic anhydrase 7 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration method [AID616474, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
9
[SID103164735]
Ki 0.0025Inhibition of human recombinant CAH7 [AID593734, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
10
[SID103164735]
Ki 0.0025Inhibition of human recombinant cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assay [AID603070, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
11
[SID103164735]
Ki 0.0025Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration method [AID600082, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
12
[SID103164735]
Ki 0.0025Inhibition of human carbonic anhydrase 7 preincubated with compound for 15 mins by carbon dioxide hydration assay [AID601815, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
13
[SID103164735]
Ki 0.0025Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration method [AID496920, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
14
[SID103164735]
Ki 0.0025Inhibition of human recombinant carbonic anhydrase 7 after 15 mins by stopped-flow CO2 hydration assay [AID493890, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
15
[SID103164735]
Ki 0.0025Inhibition of human recombinant full length CA7-mediated CO2 hydration preincubated for 15 mins by stopped-flow assay [AID669485, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
16
[SID103164735]
Ki 0.0025Ki value against human carbonic anhydrase VII [AID238315, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
17
[SID103164735]
Ki 0.0025Inhibition of full length human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assay [AID484161, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
18
[SID103164735]
Ki 0.0025Inhibition of human recombinant CA7 by stopped flow CO2 hydrase assay [AID441712, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
19
[SID103164735]
Ki 0.0025Inhibition of human full length cytosolic carbonic anhydrase 7 after 15 mins by stopped-flow CO2 hydration assay [AID438007, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
20
[SID103164735]
Ki 0.0025Inhibition of human recombinant full length CA7 by stopped flow CO2 hydration assay [AID417832, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
21
[SID103164735]
Ki 0.0025Inhibition of human carbonic anhydrase 7 by CO2 hydration assay [AID396642, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
22
[SID103164735]
Ki 0.0025Inhibition of human recombinant full length CA7 by stopped-flow CO2 hydration method [AID367615, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
23
[SID103164735]
Ki 0.0025Inhibition of human cloned CA7 by stopped-flow CO2 hydration method [AID365985, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
24
[SID103164735]
Ki 0.0025Inhibition of human carbonic anhydrase 7 by stopped-flow CO2 hydration assay [AID342482, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
25
[SID103164735]
Ki 0.0025Inhibition of human full length carbonic anhydrase 7 by stopped flow CO2 hydrase assay [AID327765, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
26
[SID103164735]
Ki 0.0025Inhibition of human recombinant carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration method [AID492422, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
27
[SID103164735]
Ki 0.0027Inhibition of S-glutathionylated form of human recombinant carbonic anhydrase 7 using carbon-dioxide as substrate preincubated for 10 mins prior to substrate addition by stopped flow cytometry [AID646243, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
28
[SID103164735]
Ki 0.0028Inhibition of human recombinant carbonic anhydrase 7 using carbon-dioxide as substrate preincubated for 10 mins prior to substrate addition by stopped flow cytometry [AID646241, Type: Literature]Carbonic anhydrase 7 [gi:1168744]
View
29
[SID103164735]
Ki 0.003Inhibition of human recombinant carbonic anhydrase 7 C183S/C217S mutant using carbon-dioxide as substrate preincubated for 10 mins prior to substrate addition by stopped flow cytometry [AID646242, Type: Literature]
View
30
[SID103164735]
Ki 0.0031Inhibition of human carbonic anhydrase 3 [AID311025, Type: Literature]Carbonic anhydrase 3 [gi:134047703]
View
31
[SID103164735]
Ki 0.0033Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assay [AID239220, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
32
[SID103164735]
IC50 0.003450% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation for 4 min at 37 degree C [AID47729, Type: Literature]
View
33
[SID103164735]
IC50 0.0034Inhibitory activity towards Carbonic anhydrase II [AID47751, Type: Literature]
View
34
[SID103164735]
Ki 0.0045Inhibition of Sulfurihydrogenibium yellowstonense YO3AOP1 alpha-carbonic anhydrase-catalyzed CO2 hydration reaction preincubated for 15 mins by stopped flow CO2 hydrase assay [AID677270, Type: Literature]
View
35
[SID103164735]
Ki 0.0057Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay [AID486935, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
36
[SID103164735]
Ki 0.0057Inhibition of human recombinant carbonic anhydrase 12 after 15 mins by stopped-flow CO2 hydration assay [AID493892, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
37
[SID103164735]
Ki 0.0057Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration method [AID496922, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
38
[SID103164735]
Ki 0.0057Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assay [AID512004, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
39
[SID103164735]
Ki 0.0057Inhibition of human recombinant CA12 catalytic domain by CO2 hydration assay [AID598015, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
40
[SID103164735]
Ki 0.0057Inhibition of human carbonic anhydrase XII by spectrophotometry at pH 7.5 [AID577529, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
41
[SID103164735]
Ki 0.0057Inhibition of tumor-associated human carbonic anhydrase 12 preincubated for 15 min by CO2 hydration assay [AID587002, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
42
[SID103164735]
Ki 0.0057Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration method [AID610538, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
43
[SID103164735]
Ki 0.0057Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay [AID614108, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
44
[SID103164735]
Ki 0.0057Inhibition of human recombinant catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydration assay [AID603451, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
45
[SID103164735]
Ki 0.0057Inhibition of human cloned CA12 catalytic domain by stopped flow CO2 hydration assay [AID441209, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
46
[SID103164735]
Ki 0.0057Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped-flow CO2 hydration assay [AID446439, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
47
[SID103164735]
Ki 0.0057Inhibition of human recombinant CA12 by stopped flow CO2 hydrase assay [AID441714, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
48
[SID103164735]
Ki 0.0057Inhibition of human membrane-bound carbonic anhydrase 12 catalytic domain after 15 mins by stopped-flow CO2 hydration assay [AID438009, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
49
[SID103164735]
Ki 0.0057Inhibitory activity against human Carbonic anhydrase XII (hCA XII) [AID254245, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View
50
[SID103164735]
Ki 0.0057Inhibitory activity against cloned human CA12 [AID258733, Type: Literature]Carbonic anhydrase 12 [gi:5915866]
View